Results 151 to 160 of about 36,796 (269)

Payload‐Based Clinical Pharmacology Review of Approved Antibody–Drug Conjugates: Commonalities and Considerations for Streamlined Development

Clinical Pharmacology &Therapeutics, EarlyView.
Antibody–drug conjugates (ADCs) combine the specificity of an antibody with the potency of a cytotoxic drug. Thirteen ADCs, utilizing seven unique cytotoxic payloads and targeting 11 distinct antigens, are currently approved by the US Food and Drug Administration as of June 2025, representing a rapidly growing and highly promising class of anticancer ...
Sijie Lu, Qingqing Xiao, Lixuan Qian, Siyuan Sun, Zhu Zhou, Michael Z. Liao, Chunze Li   +6 more
wiley   +1 more source

Case Report: History-Indicated McDonald's Cerclage for Uterine Didelphys and History of Cervical Insufficiency. [PDF]

Case Rep Obstet Gynecol
Rominger E, Lesser HT, Boozarjomehri F.
europepmc   +1 more source

Characteristic impairment of progesterone response in cultured cervical fibroblasts obtained from patients with refractory cervical insufficiency. [PDF]

Sci Rep, 2023
Sugita Y, Kuwabara Y, Katayama A, Matsuda S, Manabe I, Suzuki S, Oishi Y.   +6 more
europepmc   +1 more source

Spatiotemporal cellular dynamics of the notochord shape intervertebral disc morphogenesis in the mouse embryo through apoptosis and proliferation

Developmental Dynamics, EarlyView.
Abstract Background The notochord is a midline structure essential for vertebrate embryogenesis, contributing to the development of the nervous system, digestive tract, and vertebral column. In particular, notochord signaling is indispensable for proper patterning and coordinated development of alternating vertebrae and intervertebral discs (IVDs ...
Julie Warin, Estelle Balissat, Pauline Colombier, Lily Paillat, Maeva Dutilleul, Anne Camus   +5 more
wiley   +1 more source

Development and validation of a predictive model for cervical insufficiency incorporating AMH and androstenedione. [PDF]

Sci Rep
Zhao X, Ma M, Liu Y, Ma Y, Li R, Wang Y.
europepmc   +1 more source

Comparison of emergency cervical cerclage and expectant treatment in cervical insufficiency in singleton pregnancy: A meta-analysis. [PDF]

PLoS One, 2023
Wei Y, Wang S.
europepmc   +1 more source

Novel Noninvasive Broad‐Spectrum Infrared Treatment of Ulcerative Colitis by Modulating T‐Cell Relocation

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
A novel graphene‐based broad‐spectrum infrared (BSIR) device is developed for the noninvasive treatment of ulcerative colitis (UC). BSIR irradiation effectively alleviates colonic inflammation and accelerates mucosal recovery by inducing the systemic relocation of T lymphocytes to the spleen.
Siyu Chen, Jiangtao Zhao, Bohan Jia, Zhigang Ren, Ranran Sun, Liwen Liu, Ding Zhang, Yanqiu Fu, Jia Yu, Shen Shen, Fujun Miao, Zaimei Huang, Ruixia Guo, Peng Zhang, Zujiang Yu, Guosheng Shao   +15 more
wiley   +1 more source

Reply: Intraamniotic infection/inflammation in threatened midtrimester miscarriage, cervical insufficiency, and preterm labor without cervical changes. [PDF]

Am J Obstet Gynecol, 2023
Yoon BH, Romero R, Oh KJ, Kim HJ, Jung E, Gotsch F, Suksai M.   +6 more
europepmc   +1 more source

Transendocardial injection of expanded autologous CD34+ cells after myocardial infarction: Design of the EXCELLENT trial

ESC Heart Failure, Volume 12, Issue 2, Page 1455-1463, April 2025.
Abstract Aims The extent of irreversible cardiomyocyte necrosis after acute myocardial infarction (AMI) is a major determinant of residual left ventricular (LV) function and clinical outcome. Cell therapy based on CD34+ cells has emerged as an option to help repair the myocardium and to improve outcomes.
Jerome Roncalli, François Roubille, Nicolas Meyer, Giulio Pompilio, Lionel Leroux, Philippe Henon, Guillaume Trebuchet, Anthony Criquet, Matthieu de Kalbermatten, Eric Saloux, Alain Manrique, Pierre‐Yves Marie, Deepak L. Bhatt, Scott D. Solomon, Gilles Montalescot, David E. Newby, Faiez Zannad, on behalf of the EXCELLENT Trial Investigators   +17 more
wiley   +1 more source

Laparoscopic Cerclage in a Case of Unicornuate Uterus with Cervical Insufficiency and Previous Failed Mc Donald Cerclage with a Successful Outcome: A Case Report. [PDF]

J Obstet Gynaecol India, 2023
Sodhi M, Gupta P, Kriplani I, Kriplani A.   +3 more
europepmc   +1 more source