Cervical intraepithelial neoplasia. Clinical analysis
Cervical intraepithelial neoplasia (CIN) is the most relevant topic in cervicology due to the risk of progression to cervical cancer and its rejuvenation.
Tatiana V. Klinyshkova +1 more
doaj +2 more sources
Active surveillance of cervical intraepithelial neoplasia and adverse pregnancy outcomes: A register-based cohort study. [PDF]
Active surveillance for cervical intraepithelial neoplasia grade 2 is not associated with increased risks of adverse pregnancy outcomes compared to large loop excision of the transformation zone. Abstract Introduction Previous studies have suggested that human papillomavirus (HPV) and HPV‐related disease may be associated with increased risk of adverse
Katholm KK +6 more
europepmc +2 more sources
Risk of prostate cancer after isolated high-grade prostatic intraepithelial neoplasia (HGPIN) detected on extended core needle biopsy : a UK hospital experience. [PDF]
Background High-grade prostatic intraepithelial neoplasia (HGPIN) is a precursor lesion to prostate cancer (CaP). UK-based studies examining the occurrence of isolated HGPIN and subsequent risk of CaP are lacking.
Singh, Paras B. +5 more
core +5 more sources
TP53 polymorphism, HPV infection, and risk of cervical cancer. [PDF]
The role of a polymorphism at position 72 of the tumor suppressor gene TP53 in the development of cervical cancer is not well established. The arginine variant of the p53 protein could be more susceptible to degradation by human papillomavirus (HPV) E6 ...
Hainaut, P +11 more
core +4 more sources
Neoplasia of the cervix represents one of the most common cancers in women. Clinical and molecular research has identified immunological impairment in squamous intraepithelial cervical lesions and cervical cancer patients.
Yenddy N. Carrero +2 more
doaj +1 more source
The possible role of bacterial vaginosis in the pathogenesis of cervical precancerous lesions
The role of papillomavirus infection in the development of precancerous diseases and cervical cancer is known. Bacterial vaginosis was found to induce the deficiency of immune response of the vaginal mucosa surface.
Kemine Uzel, Igor Lakhno
doaj +1 more source
Prevention of cervical intraepithelial neoplasia and cervical cancer [PDF]
We review the current status of prevention trials in the management of cervical intraepithelial neoplasia (CIN) and cervical cancer. Two large, randomized controlled trials have shown that folic acid is inactive in reversing low to moderate grade CIN.
Meyskens, F L, Jr, Manetta, A
openaire +5 more sources
Introduction. As is known, the development of invasive cervical cancer is preceded by cervical intraepithelial neoplasia of varying severity, which is a pathological process in which cells with varying degrees of atypia and impaired differentiation ...
L. V. Tkachenko +4 more
doaj +1 more source
Associations Between Methylation of Paternally Expressed Gene 3 (PEG3), Cervical Intraepithelial Neoplasia and Invasive Cervical Cancer. [PDF]
Cytology-based screening for invasive cervical cancer (ICC) lacks sensitivity and specificity to discriminate between cervical intraepithelial neoplasia (CIN) likely to persist or progress from cases likely to resolve.
Bartlett, John A. +53 more
core +2 more sources
Risk factors for cervical intraepithelial neoplasia [PDF]
To evaluate risk factors for cervical intraepithelial neoplasia (CIN), data were collected in a case-control study based on 366 patients (58 with CIN class 1, 70 with CIN class 2, and 238 with CIN class 3) and 323 control subjects with normal cervical smears interviewed on selected days at the same screening clinics where cases had been identified.
F. Parazzini +5 more
openaire +4 more sources

