Preliminary stop of the TOPical Imiquimod treatment of high-grade Cervical intraepithelial neoplasia (TOPIC) trial [PDF]
The "TOPical Imiquimod treatment of high-grade Cervical intraepithelial neoplasia" (TOPIC) trial was stopped preliminary, due to lagging inclusions. This study aimed to evaluate the treatment efficacy and clinical applicability of imiquimod 5% cream in ...
Beekhuizen, H.J. (Heleen) van+12 more
core +1 more source
Gankyrin is frequently overexpressed in cervical high grade disease and is associated with cervical carcinogenesis and metastasis. [PDF]
Our previous studies have showed that Gankyrin expression is correlated with a malignant phenotype in endometrial carcinoma. Here, we investigated the possible role of Gankyrin in cervical disease. The increasing protein level of Gankyrin was observed in
Yuan Liu+9 more
doaj +1 more source
Cervical intraepithelial neoplasia. Clinical analysis
Cervical intraepithelial neoplasia (CIN) is the most relevant topic in cervicology due to the risk of progression to cervical cancer and its rejuvenation.
Tatiana V. Klinyshkova +1 more
doaj +1 more source
Computer-Aided Diagnosis of Label-Free 3-D Optical Coherence Microscopy Images of Human Cervical Tissue [PDF]
Objective: Ultrahigh-resolution optical coherence microscopy (OCM) has recently demonstrated its potential for accurate diagnosis of human cervical diseases. One major challenge for clinical adoption, however, is the steep learning curve clinicians need to overcome to interpret OCM images.
arxiv +1 more source
Prevalence and Associated Factors of Human Papillomavirus Infection among Iraqi Women [PDF]
Human papillomavirus (HPV) is a significant public health concern, as it is a leading cause of cervical cancer in women. However, data on the prevalence of HPV infection among Iraqi women is scarce. This study aimed to estimate the prevalence of HPV infection and its associated factors among Iraqi women aged 15-50 attending health centers.
arxiv
MicroRNA-551b expression profile in low and high-grade cervical intraepithelial neoplasia [PDF]
OBJECTIVE: To evaluate the expression of microRNA (miR)-551b in patients with low and high grade cervical intraepithelial neoplasia (CIN) and to find an association with high-risk Human Papillomavirus (HR-HPV) infection-related prognostic biomarkers ...
Bordi, G+7 more
core +1 more source
BACKGROUND: Acute phase reactants play a role in the progression and prognosis of many malignant and premalignant tumors. This study investigated the diagnostic value of certain reactants as markers for cervical premalignant lesions. OBJECTIVES: Despite
Yeliz Acar Sabır+2 more
doaj +1 more source
Screening for cervical intraepithelial neoplasia [PDF]
EDITOR, - J Elizabeth Macgregor and colleagues show that the incidence of invasive cervical cancer fell sharply in women aged 40-69 who had been well screened and had had the opportunity of repeat screening.1 Screening was associated with a tendency to present at an earlier stage.
openaire +3 more sources
HPV vaccination of immunocompromised hosts. [PDF]
It is well-established that immunocompromised people are at increased risk of HPV-related disease compared with those who are immunocompetent. Prophylactic HPV sub-unit vaccines are safe and immunogenic in immunocompromised people and it is strongly ...
Bhatla, N+9 more
core +3 more sources
Etiology and pathogenesis of cervical intraepithelial neoplasia (review of foreign literature)
Cervical intraepithelial neoplasia (CIN) is atypical transformation of squamos epithelium without stromal invasion predictive of cervical cancer. According to the World Health Organization (2014), there is mild cervical epithelial neoplasia (CIN I; mild
S. A. Levakov+2 more
doaj +1 more source