Results 51 to 60 of about 90,882 (307)

Sentinel lymphatic mapping among women with early-stage cervical cancer: A systematic review

Taiwanese Journal of Obstetrics & Gynecology, 2018
The presence of pelvic lymph node metastases is without doubt the most significant prognostic factor that determines recurrences and survival of women with early-stage cervical cancer.
Jerry Cheng-Yen Lai, Kuan-Ju Lai, Edward Yi-Yung Yu, Sho-Ting Hung, Chia-Ying Chu, Kung-Liahng Wang   +5 more
doaj   +1 more source

Role of Contrast-Enhanced Ultrasound (CEUS) in the Diagnosis of Cervical Lymph Node Metastasis in Nasopharyngeal Carcinoma (NPC) Patients

Frontiers in Oncology, 2020
Objective: The aim of the study was to evaluate the diagnostic value of contrast-enhanced ultrasound (CEUS) in distinguishing between benign and malignant cervical lymph nodes in patients with nasopharyngeal carcinoma (NPC).Material and Methods: A total ...
Wenwu Ling, Ji Nie, Ji Nie, Dingyue Zhang, Qianru Yang, Hongyu Jin, Hongyu Jin, Xuejin Ou, Xuelei Ma, Yan Luo   +9 more
doaj   +1 more source

GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy

Advanced Science, EarlyView.
Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu, Yuchen Xiao, Yamin Zhao, Lihe Dai, David J.H. Shih, Shikang Liang, Honglei Tian, Liu Liu, Feng Tian, Bing Liu, Lei Chang, Chao Zhang   +11 more
wiley   +1 more source

Sonographic assessment of normal cervical lymph nodes in a sample of Syrian population

Journal of Baghdad College of Dentistry, 2014
Background: Sonographic examination is an important tool in assessment of normal and abnormal cervical lymph nodes. The aim of the study is to assess the distribution and the characteristic features of normal cervical lymph nodes in a sample of Syrian ...
Rand Sh Al-Ani, Ammar M Mashlah, Mohammad Iyad Al-Hafar   +2 more
doaj  

A Supramolecular Nanoscavengers: Based “Cargo‐Exchange” Breaking Cholesterol Metabolic Dysregulation for Glioblastoma Therapy

Advanced Science, EarlyView.
Dysregulated cholesterol metabolism, driven by a complex array of mechanisms, is a defining characteristic of glioblastoma (GBM). In this study, supramolecular nanoscavengers are engineered by harnessing the intrinsic binding affinity between endogenous small‐molecule cholesterol and β‐cyclodextrin (β‐CD).
Zonghua Tian, Yun Chen, Jingyi Zhou, Shilin Zhang, Hongrui Fan, Xuwen Li, Tao Sun, Chen Jiang   +7 more
wiley   +1 more source

Colorectal Cancer Cell's Weapon: RNF32 Engages SPP1+ Macrophages to Foster Liver Metastasis, Targeted by Indole‐3‐Acetic Acid

Advanced Science, EarlyView.
Cytoplasmic RNF32 fuels CRC liver metastasis by degrading GSK3β, which stabilizes β‐catenin and activates Wnt/EMT. Moreover, RNF32 rewires the metastatic niche: it depletes CD8+/CD4+ T and NK cells while recruiting SPP1+ macrophages (which boost tumor stemness via CD44), fibroblasts, and immunosuppressive monocytes to aid colonization.
Hongyu Wang, Shipeng Dai, Yuchen Xie, Pengyu Chen, Yue Chai, Chongyu Wang, Xueying Huang, Xiao Dong, Junfeng Shi, Yongxiang Xia, Xiaofeng Qian, Weiwei Tang, Yichan Zhou   +12 more
wiley   +1 more source

Case Report: A case of micropapillary thyroid carcinoma with level I cervical lymph node metastasis

Frontiers in Oncology
Papillary thyroid carcinoma frequently metastasizes to cervical lymph nodes, particularly involving the central and lateral compartments. Metastasis to upper mediastinal lymph nodes is also not unusual.
Qi Yang, Wei Cheng, Qin-long Liang, Li Yan   +3 more
doaj   +1 more source

T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities

Advanced Science, EarlyView.
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu, Xiaoyu Yao, Qingyang Wang, Mengrui Yang, Runze Li, Jiangjiang Qin, Jing Zhuang, Changgang Sun   +7 more
wiley   +1 more source

A CASE REPORT OF DIFFICULT DIAGNOSIS IN THE PATIENT WITH LARYNGEAL CANCER

Сибирский онкологический журнал, 2016
We present a case of the difficult morphological verification and ambiguous interpretation of immunohistochemical examination of cervical lymph nodes metastases from unknown primary tumor with late clinical diagnosis of laryngeal cancer.
D. V. Gavrilyuk, M. V. Avdeenko, R. A. Zukov, S. Yu. Chizhevskaya   +3 more
doaj   +1 more source

Photoacoustic Microscopy for Multiscale Biological System Visualization and Clinical Translation

Advanced Science, EarlyView.
Photoacoustic microscopy (PAM) is a powerful biomedical imaging tool renowned for its non‐invasiveness and high resolution. This review synthesizes recent technological advances and highlights their broad applications from cellular and organ‐level to whole‐animal imaging.
Tingting Wang, Jiali Chen, Liming Nie, Honghui Li   +3 more
wiley   +1 more source