Results 91 to 100 of about 317,051 (282)

IMOP: randomised placebo controlled trial of outpatient cervical ripening with isosorbide mononitrate (IMN) prior to induction of labour – clinical trial with analyses of efficacy, cost effectiveness and acceptability

open access: yesBMC Pregnancy and Childbirth, 2006
Background There is increasing interest in carrying out pre-induction cervical ripening on an outpatient basis. However, there are concerns about the use of prostaglandins, the agents commonly used in hospital settings for this indication, because ...
Greer Ian   +7 more
doaj   +1 more source

Deep Learning Pose Estimation for Phenotyping of Co‐Occurring Hyperkinetic Movement Disorders

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore whether routine outpatient video combined with deep learning‐based pose estimation and clinically interpretable kinematic features can support multi‐label phenotyping of co‐occurring hyperkinetic movement disorders (HMDs).
Laura Cif   +17 more
wiley   +1 more source

Corticosteroids for cervical ripening and induction of labour

open access: yesCochrane Database of Systematic Reviews, 2006
The role of corticosteroids in the process of labour is not well understood. Animal studies have shown the importance of cortisol secretion by the fetal adrenal gland in initiating labour in sheep. Infusion of glucocorticosteroids into the fetus has also shown to induce premature labour in sheep.
J, Kavanagh, A J, Kelly, J, Thomas
openaire   +3 more sources

Cervical screening in Australia 2010-2011 [PDF]

open access: yes, 2013
This paper presents the latest national statistics monitoring the National Cervical Screening Program, which aims to reduce incidence, morbidity and mortality from cervical cancer.Summary:The National Cervical Screening Program (NCSP) aims to reduce

core  

Progressive Parkinsonism in PPP2R5D‐Related Neurodevelopmental Disorder

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT PPP2R5D‐related neurodevelopmental disorder (Houge–Janssens syndrome type 1) is a rare autosomal dominant condition characterized by macrocephaly, intellectual disability, and epilepsy. Progressive parkinsonism is an emerging adult phenotype that neurologists should be aware of since timely genetic diagnosis opens the door to disease‐modifying
Katerina Bernardi   +6 more
wiley   +1 more source

Isosorbide mononitrate for preinduction cervical ripening at or post-term pregnancy: randomised placebo-controlled clinical trial

open access: yesGynecology and Obstetrics Clinical Medicine
Introduction Effective labour induction is marked by the onset of uterine contractions, progressive cervical dilation, and effacement, culminating in a vaginal birth without maternal or fetal complications.
Ramy Mohamed El-Naggar   +3 more
doaj   +1 more source

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem   +9 more
wiley   +1 more source

Inhibition of Cervical Ripening Prevents Spontaneous Preterm Birth [PDF]

open access: yes, 2005
Background The preterm birth remains one of the important factors and causes that may influence the neonatal morbidity and mortality. Recent research has shown the significant roles of the inflammatory cytokine systems as IL-8 and PGE2 receptors (EP1 ...
杉村, 基
core   +1 more source

Vaginal microbiota in term pregnant women with differences in cervical ripeness revealed by 2bRAD-M

open access: yesBMC Microbiology
Background Cervical ripening is a multifactorial outcome, and the association between cervical ripening and vaginal microbiota remains unexplored in term primiparous women.
Saihu Lu   +6 more
doaj   +1 more source

Associations Between Methylation of Paternally Expressed Gene 3 (PEG3), Cervical Intraepithelial Neoplasia and Invasive Cervical Cancer. [PDF]

open access: yes, 2013
Cytology-based screening for invasive cervical cancer (ICC) lacks sensitivity and specificity to discriminate between cervical intraepithelial neoplasia (CIN) likely to persist or progress from cases likely to resolve.
Bartlett, John A.   +53 more
core   +2 more sources

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