Results 101 to 110 of about 222,210 (341)

Motor deficits and recovery in rats with unilateral spinal cord hemisection mimic the Brown-Séquard syndrome [PDF]

, 2017
Cervical incomplete spinal cord injuries often lead to severe and persistent impairments of sensorimotor functions and are clinically the most frequent type of spinal cord injury.
Filli, Linard, Schwab, Martin E., Weinmann, Oliver, Zörner, Björn   +3 more
core  

Anatomical and molecular properties of long descending propriospinal neurons in mice [PDF]

, 2017
Long descending propriospinal neurons (LDPNs) are interneurons that form direct connections between cervical and lumbar spinal circuits. LDPNs are involved in interlimb coordination and are important mediators of functional recovery after spinal cord ...
Boyle, Kieran, Callister, Robert J., Conn, Victoria, Flynn, Jamie R., Goulding, Martyn D., Graham, Brett A., Hughes, David I., Velasquez, Tomoko, Watanabe, Masahiko   +8 more
core   +1 more source

Clinical Trial of Human Fetal Brain-Derived Neural Stem/Progenitor Cell Transplantation in Patients with Traumatic Cervical Spinal Cord Injury

Journal of Neural Transplantation and Plasticity, 2015
In a phase I/IIa open-label and nonrandomized controlled clinical trial, we sought to assess the safety and neurological effects of human neural stem/progenitor cells (hNSPCs) transplanted into the injured cord after traumatic cervical spinal cord injury
J. Shin, Keung Nyun Kim, Jeehyun Yoo, Il-Sun Kim, Seokhwan Yun, Hyejin Lee, Kwangsoo Jung, Kyujin Hwang, Miri Kim, Il-Shin Lee, Jeong-eun Shin, Kook In Park   +11 more
semanticscholar   +1 more source

RPS3‐Enriched Extracellular Vesicles Mediate Liver‐Spinal Cord Inter‐Organ Communication

Advanced Science, EarlyView.
Spinal cord injury activates the liver to send extracellular vesicles loaded with RPS3 protein to the lesion site. These vesicles are taken up by neural stem cells and astrocytes, triggering NF‐κB signaling, impairing the regeneration of neurons and myelin, and promotes harmful inflammation, ultimately hindering recovery.
Peiwen Song, Zuomeng Wu, Yixiang Dong, Yunxiong Fang, Shiyu Bian, Daokuan Wang, Huang Fang, Yunlei Liu, Wang Ying, Jun Qian, Tianyu Han, Cailiang Shen   +11 more
wiley   +1 more source

Research progress on application of lung rehabilitation concept in nursing care of patients with cervical spinal cord injury

Huli yanjiu, 2017
It introduced the changes of pulmonary function in patients with cervical spinal cord injury,and pointed out that the opportunity and indication should be seized in the implementation of pulmonary rehabilitation,Lung rehabilitation includes pre ...
解雨, 刘蕾, 何海燕, 祝晓迎, 曾登芬   +4 more
doaj  

Alterations in Cortical Sensorimotor Connectivity following Complete Cervical Spinal Cord Injury: A Prospective Resting-State fMRI Study

PLoS ONE, 2016
Functional magnetic resonance imaging (fMRI) studies have demonstrated alterations during task-induced brain activation in spinal cord injury (SCI) patients.
A. Oni-Orisan, M. Kaushal, Wenjun Li, Jack Leschke, B. D. Ward, A. Vedantam, Benjamin Kalinosky, M. Budde, B. Schmit, Shi-Jiang Li, Vaishnavi Muqeet, S. Kurpad, M. Fehlings   +12 more
semanticscholar   +1 more source

Remote Activation of Spinal TRPV1 by Magnetic Nanocubes Confers Cardioprotection Against Myocardial Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
Fe‐based magnetic nanocubes conjugated with TRPV1 antibodies (FeNCs‐TRPV1) are developed for the specific targeting of TRPV1 channels. Intraspinally injected FeNCs‐TRPV1 induces TRPV1 desensitization in rats exposed to repetitive and transient ACMF.
Xueying Cheng, Shuangyu Liu, Yu Zhang, Kang Peng, Muge Qile, Chao Wu, Mengyun Dou, Liu Liu, Na Yang, Rui Liu, Guiyang Zhang, Liangping Ni, Gaolin Liang, Fang Yang, Ye Zhang, Shufang He   +15 more
wiley   +1 more source

Evidence-based commentary on the diagnosis, management, and further research of degenerative cervical spinal cord compression in the absence of clinical symptoms of myelopathy

Frontiers in Neurology
Degenerative cervical myelopathy (DCM) represents the final consequence of a series of degenerative changes in the cervical spine, resulting in cervical spinal canal stenosis and mechanical stress on the cervical spinal cord.
Tomas Horak, Tomas Horak, Magda Horakova, Magda Horakova, Milos Kerkovsky, Milos Kerkovsky, Marek Dostal, Marek Dostal, Petr Hlustik, Petr Hlustik, Jan Valosek, Jan Valosek, Jan Valosek, Jan Valosek, Alena Svatkova, Alena Svatkova, Petr Bednarik, Petr Bednarik, Eva Vlckova, Eva Vlckova, Josef Bednarik, Josef Bednarik   +21 more
doaj   +1 more source

Diffusion Tensor Imaging Correlates with Short-Term Myelopathy Outcome in Patients with Cervical Spondylotic Myelopathy [PDF]

, 2017
Objective To determine if spinal cord diffusion tensor imaging indexes correlate with short-term clinical outcome in patients undergoing elective cervical spine surgery for cervical spondylotic myelopathy (CSM).
Eckardt, Gerald, Jirjis, Michael B., Kurpad, Shekar N., Rao, Avinash, Schmit, Brian D., Vedantam, Aditya, Wang, Marjorie C.   +6 more
core   +2 more sources

Exploring the Vasculitis‐Tumors Link: Epidemiological Patterns, Mechanistic Insights, and Clinical Implications

Advanced Science, EarlyView.
This review outlines association between vasculitis and malignancies and provides practical value for clinicians in distinguishing primary vasculitis from malignancy‐associated forms and optimizing patient surveillance, improving recognition of tumor‐associated vasculitis to reduce the risk of misdiagnosis, supporting more accurate clinical decision ...
Xiaofei Shi, Zhijiao Li, Xin Ma, Bei Zhang, Xinfeng Wu, Hua Fan, Rongzeng Liu, Hongwei Jiang, Cong‐Qiu Chu   +8 more
wiley   +1 more source