Results 161 to 170 of about 91,569 (275)

Effect of Interleukin‐6 Inhibitors on Rheumatoid Arthritis Pain: Overview of Evidence and Mechanistic Pathways

open access: yesPharmacology Research &Perspectives, Volume 14, Issue 2, April 2026.
This review synthesizes current mechanistic and clinical evidence on IL‐6 inhibitors, particularly sarilumab and tocilizumab, concerning their effect on pain in RA. ABSTRACT Rheumatoid arthritis (RA) is an autoimmune systemic disease in which pain remains a major and often refractory symptom even after clinical remission of the disease.
Andrej Belančić   +10 more
wiley   +1 more source

Network Pharmacology Combined With Clinical Retrospective Analysis to Investigate the Potential Mechanisms and Clinical Significance of Folate in Treating Spinal Cord Injury

open access: yesPharmacology Research &Perspectives, Volume 14, Issue 2, April 2026.
ABSTRACT Folate is an indispensable nutrient involved in key biological processes, including enzymatic reactions, DNA replication, metabolic regulation, and methylation. Studies indicate that folate promotes neuronal regeneration and repair in patients with spinal cord injury (SCI); however, its precise mechanisms remain unclear.
Xiaolei Chu   +7 more
wiley   +1 more source

Feasibility of Telehealth‐Delivered Electrotherapy for Neurogenic Bladder Care in Aotearoa New Zealand

open access: yesJournal of the Royal Society of New Zealand, Volume 56, Issue 2, April 2026.
Introduction: Neurogenic lower urinary tract dysfunction (NLUTD) is a major complication of spinal cord injury (SCI), yet access to specialist bladder care remains limited in many regions of Aotearoa New Zealand. Transcutaneous electrostimulation of sacral dermatomes (TESD) is a non‐invasive neuromodulation approach that can be delivered remotely ...
Tassanai Parittotokkaporn   +5 more
wiley   +1 more source

Non-cervical diffuse idiopathic skeletal hyperostosis is a risk factor for severe cervical spinal cord injury. [PDF]

open access: yesBMC Musculoskelet Disord
Nakata T   +8 more
europepmc   +1 more source

Corticospinal, reticulospinal and motoneuronal contributions to fatigability during a sustained contraction of the elbow flexors

open access: yesExperimental Physiology, Volume 111, Issue 4, Page 2190-2199, 1 April 2026.
Abstract Synaptic input to the motoneuron pool is altered during fatiguing muscle contractions. In humans, the corticospinal tract is often studied, with equivocal findings regarding its role in the reduction of force. To date, the involvement of the reticulospinal tract during states of fatigue has not been explored.
Oliver Hayman   +8 more
wiley   +1 more source

Acute cardio‐centric haemodynamic management preserves chronic cardiovascular function in pigs with high‐thoracic spinal cord injury

open access: yesThe Journal of Physiology, Volume 604, Issue 7, Page 2659-2682, 1 April 2026.
Abstract figure legend Recent work has shown that treating the reduction in heart function following acute spinal cord injury (SCI) better optimizes peripheral haemodynamics and spinal cord oxygenation than the standard approach of using vasopressors.
Alexandra M. Williams   +13 more
wiley   +1 more source

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