Results 51 to 60 of about 1,488,516 (293)

Utilizing multimodal radiomics technology from cervical MRI for diagnosis of cervical spinal cord injury and spinal cord concussion

Scientific Reports
The primary aim of this study is to assess the viability of employing multimodal radiomics techniques for distinguishing between cervical spinal cord injury and spinal cord concussion in cervical magnetic resonance imaging.
Zhigang Pan, Weipeng Hu, Zhangsheng Dai, Yuanzhe Li, Zhongning Fang, Canfang Shen, Zekai Chen, Kaibin Fang   +7 more
doaj   +1 more source

Trihydroxyethyl Rutin Provides Neuroprotection in Rats With Cervical Spinal Cord Hemi-Contusion

Frontiers in Neuroscience, 2021
Objective: To investigate the neuroprotective effects of trihydroxyethyl rutin in rats with cervical spinal cord hemi-contusion.Methods: Adult male Sprague–Dawley rats were subjected to hemi-contusion at a stroke depth of 1.2 mm, and then ...
Yapu Liu, Yapu Liu, Qi Liu, Zhou Yang, Rong Li, Zhiping Huang, Zucheng Huang, Junhao Liu, Xiuhua Wu, Junyu Lin, Xiaoliang Wu, Qingan Zhu   +11 more
doaj   +1 more source

Transplantation of olfactory ensheathing cells into spinal cord lesions restores breathing and climbing [PDF]

, 2003
One of the most devastating effects of damage to the upper spinal cord is the loss of the ability to breathe; patients suffering these injuries can be kept alive only with assisted ventilation. No known method for repairing these injuries exists.
Raisman, G., Li, Y., Decherchi, P.
core  

Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird, Haley McQuown, Jihyun Park, Samuel J. Teener, Ian F. Webber‐Davis, Andrew D. Carter, Dae‐Gyu Jang, Eva L. Feldman, Stephen A. Goutman, Benjamin J. Murdock   +9 more
wiley   +1 more source

A Blood‐Derived Factor Rescues ALS: Platelet Factor 4 Activates OPTN‐Dependent Autophagy to Clear SOD1 Aggregates Independently of PINK1

Advanced Science, EarlyView.
Systemic platelet factor 4 (PF4) is significantly depleted in amyotrophic lateral sclerosis (ALS). Peripheral PF4 replenishment restores central proteostasis by driving OPTN‐dependent, PINK1‐independent selective autophagy in motor neurons. This intervention effectively clears toxic SOD1 aggregates, blunts glial activation, and preserves neuromuscular ...
Qingjian Xie, Yanbo Zhu, Wenhua Jiang, Haobo Xie, Yaojia Li, Mengjie Hu, Kezheng Li, Huan Yu, Yixuan Pan, Chaoyi Jiang, Xueqin Song, Dongsheng Fan, Binbin Deng   +12 more
wiley   +1 more source

Iatrogenic Spinal Cord Injury Resulting From Cervical Spine Surgery

Global Spine Journal, 2017
Study Design: Retrospective cohort study of prospectively collected data. Objective: To examine the incidence of iatrogenic spinal cord injury following elective cervical spine surgery.
Alan H. Daniels MD, Robert A. Hart MD, Alan S. Hilibrand MD, David E. Fish MD, MPH, Jeffrey C. Wang MD, Elizabeth L. Lord MD, Zorica Buser PhD, P. Justin Tortolani MD, D. Alex Stroh MD, Ahmad Nassr MD, Bradford L. Currier MD, Arjun S. Sebastian MD, Paul M. Arnold MD, FACS, Michael G. Fehlings MD, PhD, Thomas E. Mroz MD, K. Daniel Riew MD   +15 more
doaj   +1 more source

Care of the hand in cervical spinal cord injuries [PDF]

Spinal Cord, 1969
The care of the hand in cervical spinal cord injury should be a well-organised programme in order to provide maximum function to the patient who is already severely disabled. The methods used should include careful examination and evaluation, attention to posture of the hand, range of motion exercises, the use of a wide variety of external aids, and ...
openaire   +2 more sources

A Hypothalamic Oxytocinergic–Sympathetic Axis Couples Anxiety Dysregulation With Impaired Tendon–Bone Repair

Advanced Science, EarlyView.
RCI is associated with functional suppression of oxytocinergic neurons in the PVN. Reduced PVNOXT neuronal activity contributes to altered sympathetic regulation involving the IML–sympathetic chain pathway, accompanied by changes in norepinephrine signaling at the BTI.
Liyang Wan, Tingmo Huang, Liyue Zeng, Ruixue Du, Hengshuo Zhang, Shen Liu, Tao Zhang, Jianzhong Hu, Hongbin Lu   +8 more
wiley   +1 more source

Functional outcome of patients with spinal cord injury: rehabilitation outcome study [PDF]

, 1999
Objective: To increase our knowledge of neurological recovery and functional outcome of patients with spinal cord injuries in order to make more successful rehabilitation programmes based on realistic goals.Design: Descriptive analysis of data gathered ...
Mulder, G.A., Schönherr, M.C., Groothoff, J.W., Eisma, W.H.   +3 more
core   +1 more source

Meningeal Lymphatic LTBR Deficiency Links Spinal Cord Injury to Secondary Brain Pathology

Advanced Science, EarlyView.
Spinal cord injury (SCI) induces remote brain alterations beyond the injured spinal cord. This study links dysfunction of meningeal lymphatic vessels (mLVs) to neuroinflammation and neuronal injury after SCI. LTBR‐mediated lymphatic restoration improves meningeal lymphatic integrity and neurological outcomes, highlighting LTBR as a potential regulator ...
Yi Chen, Yu Tang, Chengpeng Hu, Xiaoyan Duan, LingXia Min, Boya Cong, Chao Ma, Mingliang Tan, Ya Luo, Pengfei Wei, Minpeng Xu, Zhou Feng, Jingming Hou   +12 more
wiley   +1 more source