Results 251 to 260 of about 869,003 (294)

Non‐Contrast Assessment of Blood–Brain Barrier Permeability to Water: Improved Signal Modeling and Data Acquisition

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose Water‐extraction‐with‐phase‐contrast‐arterial‐spin‐tagging (WEPCAST) MRI is a non‐contrast method to estimate the blood–brain barrier (BBB) permeability to water. Similar to other arterial‐spin‐labeling (ASL) based techniques, signal‐to‐noise ratio is a limitation.
Wen Shi, Jiani Wu, Yifan Gou, Jie Song, Zhiyi Hu, Zihan Wang, Dengrong Jiang, Rebecca Veenhuis, Leah Rubin, Yulin Ge, Zixuan Lin, Hanzhang Lu   +11 more
wiley   +1 more source

Intervertebral disc degeneration, age, and sex affect the range of motion of the cervical spine. [PDF]

Sci Rep
Liebsch C, Greiner-Perth AK, Vogt M, Vieres V, Jonas R, Kienle A, Wilke HJ.   +6 more
europepmc   +1 more source

Relief of pain associated with spasticity in adult patients after treatment with onabotulinumtoxinA: Post hoc observational results from the ASPIRE study

PM&R, EarlyView.
Abstract Background Pain is often observed in patients with spasticity, but little is known about the relationship between pain and spasticity and the effectiveness of treating pain with botulinum toxins in these patients. Objective To explore onabotulinumtoxinA (onabotA) use and pain relief in patients with spasticity with pain at baseline.
Jörg Wissel, Cassandra List, Marc Schwartz, Mariana Nelson, Tiziana Musacchio, Esther Duarte   +5 more
wiley   +1 more source

Posterolateral Sulcus Approach for Intramedullary Hemorrhage Associated With Cavernous Malformation of High Cervical Spine: Operative Technique and Outcomes. [PDF]

Neurospine
Fujikawa Y, Kashiwagi H, Fukumura M, Yagi R, Hiramatsu R, Kameda M, Nonoguchi N, Furuse M, Kawabata S, Takami T, Wanibuchi M.   +10 more
europepmc   +1 more source

State‐of‐the‐Art on Model‐Informed Drug Development Approaches for Pediatric Rare Diseases

CPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT Pediatric rare diseases present unique challenges for drug development due to small patient populations, ethical constraints on clinical trial design, and limited prospectively defined natural history data. Model‐Informed Drug Development (MIDD) has emerged as a powerful paradigm to address these challenges by leveraging quantitative methods ...
Rajesh Krishna, Amitava Mitra, Matthew L. Zierhut, Lilly East, Chandra Durairaj   +4 more
wiley   +1 more source

Bone grafting in pedicle screw fixation of upper cervical spine: is it necessary? [PDF]

Int J Surg
Wang G, Xu J.
europepmc   +1 more source

Biomaterial‐Based Emergency Intervention for Secondary Spinal Cord Injury

Small Science, EarlyView.
Emergency intervention using advanced biomaterials targets key pathological mechanisms to block secondary spinal cord injury (SCI) by inhibiting inflammation, reducing excitotoxicity, restoring the blood−spinal cord barrier, and limiting scar formation, which provides significant neural protection and promotes neural regeneration, offering promising ...
Jincheng Li, Qingzheng Zhang, Zongtai Liu, Weiguo Xu, Changfeng Fu, Jianxun Ding   +5 more
wiley   +1 more source

A Comprehensive and Modality Diverse Cervical Spine and Back Musculoskeletal Physical Exam Curriculum for Medical Students. [PDF]

J Educ Teach Emerg Med
Davis K, Frank A, Alcala-Arcos T, Godenzi C, Allison M, Riggle C, Sakaria S, Nelson AM, Wray A, Kim BY.   +9 more
europepmc   +1 more source