Results 81 to 90 of about 909,951 (358)

Anterolateral Cervical Kyphoplasty for Metastatic Cervical Spine Lesions [PDF]

, 2018
Study Design Retrospective case series. Purpose To evaluate the clinical and radiological efficacy of anterolateral kyphoplasty for cervical spinal metastasis.
Zhi Wang, Ghassan Boubez, Daniel Shedid, Amer Sebaaly, Laura Masucci, Ahmed Najjar   +5 more
core   +1 more source

Imaging of Blunt Cervical Spine Ligamentous Injuries: Bridging the Gap between Neuroradiologists and Neurosurgeons

, 2023
In a setting of acute spinal trauma, imaging delineates all osseous and soft-tissue injuries and helps to guide potential surgical intervention. CT is the technique of choice in the setting of acute trauma.
Prabhu, A, Stanton, M, Bhuta, S
core   +1 more source

Interactions of Antibody Drug Conjugate Anti‐Tubulin and Topoisomerase I Inhibitor Payloads with Radiotherapy to Potentiate Immunotherapy

Advanced Science, EarlyView.
Antibody drug conjugates deliver their cytotoxic anti‐tubulin or topoisomerase I inhibitor payloads to tumors through cancer cell receptor targeting. The released drug payloads induce cellular changes that interact with radiotherapy resulting in radiosensitization that improves cancer cell kill and stimulates anti‐tumor immune responses.
Jacqueline Lesperance, Bryan S. Yung, Michael M. Allevato, Marcus M Cheng, Maria F. Camargo, Robert Saddawi‐Konefka, Kanika Dhawan, Ashwyn K. Sharma, Mahsa Mortaja, Sophie Bice, Daniel J. Scanderbeg, Diego Alvarado, Jyoti Mayadev, Ramez N. Eskander, Stephen R. Adams, Pippa F. Cosper, J. Silvio Gutkind, Sunil J. Advani   +17 more
wiley   +1 more source

The Reliabilities of Several Measurement Methods of Cervical Sagittal Alignment in Cases with Cervical Spine Rotation Using X-ray Findings in Cervical Spine Disorders

Spine Surgery and Related Research, 2018
Introduction: Several measurement methods designed to provide an understanding of cervical sagittal alignment have been reported, but few studies have compared the reliabilities of these measurement methods.
Kiyonori Yo, Eiki Tsushima, Yosuke Oishi, Masaaki Murase, Shoko Ota, Yoko Matsuda, Yusuke Yamaoki, Rie Morihisa, Takahiro Uchihira, Tetsuya Omura   +9 more
doaj   +1 more source

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

Advanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong, Yuhang Xie, Zhijie Weng, Yongzhi Wu, Longjiang Li, Bo Li   +5 more
wiley   +1 more source

Reverse-motion cervical rotation exercises improve cervical mobility: a 2-week intervention study

Frontiers in Sports and Active Living
IntroductionCervical spine mobility is essential for daily functioning, sports performance, and overall spinal health. Among cervical spine motions, rotation is most strongly associated with limitations in activities of daily living (ADL).
Koji Murofushi, Hiroshi Akuzawa, Sho Mitomo, Hiroki Katagiri, Hiroki Katagiri, Takehiro Ohmi, Kazuyoshi Yagishita, Koji Kaneoka   +7 more
doaj   +1 more source

Current status of full-endoscopic spine surgery in cervical spine: Anterior and posterior approach

Indian Spine Journal, 2020
The techniques for the treatment of cervical disc herniation and cervical myelopathy have evolved over the last two decades. Anterior cervical decompression and fusion has been considered to be the gold standard technique to date.
Sagar B Sharma, Jin-Sung Luke Kim, Naveen D Siddappa, Hussam E Jabri   +3 more
doaj   +1 more source

Cervical spine characteristics differ in competitive combat athletes compared with active control participants

, 2022
Background: Injury to the head and neck are common in combat sport athletes. Impairments of the cervical spine have been found in some athletes who participate in sports with high forces and collisions.
Leung, Felix T, Hides, Julie A, Brown, Daniel A, Evans, Kerrie, Grant, Gary   +4 more
core   +1 more source

T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities

Advanced Science, EarlyView.
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu, Xiaoyu Yao, Qingyang Wang, Mengrui Yang, Runze Li, Jiangjiang Qin, Jing Zhuang, Changgang Sun   +7 more
wiley   +1 more source

Targeting Supramolecular Active Complexes of Nav1.7/Nav1.8 to Relieve Chronic Neuropathic Pain

Advanced Science, EarlyView.
In mice and patients with severe chronic neuropathic pain (NP), Nav1.7, Nav1.8, TrkB, and five cytoskeletal proteins form supramolecular active complexes (SMACs) with polygonal lattice structures as noxious signal amplifiers in dorsal root ganglion (DRG) neurons.
Liting Sun, Hang Xian, Yunxin Shi, Taotan Yang, Hongyan Shuai, Wenchao Hu, Siying Fei, Miao Xu, Taoyuan Yang, Ruilong Xia, Ting Wen, Fengting Zhu, Yan Fu, Yang Li, Wei Xia, Ran Qian, Yuanying Liu, Zhicheng Tian, Lamei Li, Qian Zhou, Lize Xiong, Rui Cong, Ceng Luo, Shengxi Wu, Xiafeng Shen, Xin Yu, Rou‐Gang Xie, Changgeng Peng   +27 more
wiley   +1 more source