Results 161 to 170 of about 190,863 (329)

Human Cyclophilins—An Emerging Class of Drug Targets

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Cyclophilins are a family of enzymes with peptidyl‐prolyl isomerase activity found in all cells of all organisms. To date, 17 cyclophilin isoforms have been identified in the human body, participating in diverse biological processes. Consequently, cyclophilins have emerged as promising targets for drug development to address a wide array of ...
Katarina Jurkova   +3 more
wiley   +1 more source

Surgical treatment for cervical spine injury in nonagenarians: A report of three cases. [PDF]

open access: yesTrauma Case Rep, 2021
Yasukawa T   +7 more
europepmc   +1 more source

Relief of pain associated with spasticity in adult patients after treatment with onabotulinumtoxinA: Post hoc observational results from the ASPIRE study

open access: yesPM&R, EarlyView.
Abstract Background Pain is often observed in patients with spasticity, but little is known about the relationship between pain and spasticity and the effectiveness of treating pain with botulinum toxins in these patients. Objective To explore onabotulinumtoxinA (onabotA) use and pain relief in patients with spasticity with pain at baseline.
Jörg Wissel   +5 more
wiley   +1 more source

Biomaterial‐Based Emergency Intervention for Secondary Spinal Cord Injury

open access: yesSmall Science, EarlyView.
Emergency intervention using advanced biomaterials targets key pathological mechanisms to block secondary spinal cord injury (SCI) by inhibiting inflammation, reducing excitotoxicity, restoring the blood−spinal cord barrier, and limiting scar formation, which provides significant neural protection and promotes neural regeneration, offering promising ...
Jincheng Li   +5 more
wiley   +1 more source

Retro-odontoid pseudotumor with uncommon presentation of cervical spine injury. [PDF]

open access: yesAcute Med Surg, 2021
Kikuta S   +4 more
europepmc   +1 more source

Cobotic Ultrasound Systems in Obstetric Assessment: A Scoping Review

open access: yesSonography, EarlyView.
ABSTRACT Surgical subspecialties have successfully combined robotic technology with traditional practices. In doing so, they have benefited from increased precision in techniques, reduced incidence of surgical complications, and reduced MSK disorders. This scoping review aims to examine the extent of cobotics in obstetric ultrasound.
Caterina Watson   +4 more
wiley   +1 more source

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