Results 71 to 80 of about 190,863 (329)

Steroid Receptor Coactivator‐1 Drives Tumor‐Associated Macrophage Reprogramming by Mediating MMP12 Transcription in Pancreatic Cancer Perineural Invasion

Advanced Science, EarlyView.
Steroid receptor coactivator‐1 (SRC‐1) reprograms tumor‐associated macrophages (TAMs) via signal transducer and activator of transcription 1(STAT1)‐mediated matrix metallopeptidase 12 (MMP12) transcription to drive perineural invasion (PNI) in pancreatic cancer.
Ke Cheng, Liang Liu, Miaomiao Gong, Yuke Ji, Chunmei Bai, Xiangqian Guo, Hui Chen, Jinjin Pan, Ying Zhang, Yuhui Yuan   +9 more
wiley   +1 more source

Cervical vertebral and spinal cord injuries in rollover occupants

Injury Epidemiology
Background Rollover crashes continue to be a substantial public health issue in North America. Previous research has shown that the cervical spine is the most injured spine segment in rollovers, but much of the past research has focused on risk factors ...
Loay Al-Salehi, Shannon G. Kroeker, Jason R. Kerrigan, Peter A. Cripton, Matthew B. Panzer, Gunter P. Siegmund   +5 more
doaj   +1 more source

Sleep Deprivation Aggravates Periodontitis Through Trigeminal‐Periodontal Neuroimmune Pathway Mediated by the AChE‐ACh‐α7nAChR Axis

Advanced Science, EarlyView.
Sleep deprivation (SD) exacerbates ligature‐induced periodontitis (LIP) through the trigeminal nerve‐periodontal neuroimmune pathway mediated by the acetylcholinesterase (AChE)‐acetylcholine (ACh)‐α7 nicotinic receptor (α7nAChR) axis. While electroacupuncture (EA) alleviates the condition of LIP combined with SD by activating the α7nAChR.
Kehao Liu, Qi Huang, Mingcong Yang, Ziyu Huang, Kamoran Tuerhong, Yue Zu, Ying Xie, Xuehui Hu, Qianyu Zhang, Ping He, Nannan Huang, Rong Zhang, Yuzhou Li, Sheng Yang   +13 more
wiley   +1 more source

Misplaced Cervical Screws Requiring Reoperation. [PDF]

, 2017
STUDY DESIGN: A multicenter, retrospective case series. OBJECTIVE: In the past several years, screw fixation of the cervical spine has become commonplace. For the most part, this is a safe, low-risk procedure.
Arnold, Paul M., Currier, Bradford L., De Giacomo, Anthony F., Fehlings, Michael G., Fogelson, Jeremy L., Hart, Robert A., Hilibrand, Alan S., Hsu, Wellington K., Jobse, Bruce C., Massicotte, Eric M., Mroz, Thomas E., Nassr, Ahmad, Peterson, Jeremy C., Rahman, Ra\u27Kerry K., Riew, K. Daniel, Smith, Zachary A., Tannoury, Chadi A., Tannoury, Tony   +17 more
core   +2 more sources

Potentiating Cerebral Perfusion Normalizes Glymphatic Dynamics in Systemic Inflammation

Advanced Science, EarlyView.
LPS‐induced systemic inflammation increases glymphatic influx but delays cervical lymphatic drainage, accompanied by AQP4 depolarization and impaired glymphatic clearance. Enhancing cerebral blood flow via the inotropic agent levosimendan effectively restored AQP4 polarization, improving glymphatic flux and amyloid‐β clearance.
Ruoyu Zhao, Bin Sun, Pengju Wei, Yingying Sun, Qianyan He, Kejia Zhang, Jun Lu, Shoujun Zhu, Yi Yang, Zhenni Guo   +9 more
wiley   +1 more source

Mechanism and patterns of cervical spine fractures-dislocations in vertebral artery injury

Journal of Craniovertebral Junction and Spine, 2012
Purpose: To identify the fracture patterns and mechanism of injury, based on subaxial cervical spine injury classification system (SLIC), on non-contrast computed tomography (NCCT) of cervical spine predictive of vertebral artery injury (VAI).
Pankaj Gupta, Atin Kumar, Shivanand Gamangatti   +2 more
doaj   +1 more source

Upper Lumbar Pedicle Screw Insertion Using Three-Dimensional Fluoroscopy Navigation:Assessment of Clinical Accuracy [PDF]

, 2010
We used a navigation system to insert 128 pedicle screws into 69 vertebrae (L1 to L3) of 49 consecutive patients. We assessed the pedicle isthmic width and the permission angle for pedicle screw insertion. The permission angle is the angle defined by the
Ito, Yasuo, Mazaki, Tetsuro, Shimokawa, Tetsuya, Shiozaki, Yasuyuki, Sugimoto, Yoshihisa, Tanaka, Masato, Tomioka, Masao   +6 more
core   +1 more source

A Twist in the Diagnosis: Chronic Arthropathy Without Inflammation

Arthritis Care &Research, EarlyView.
María Á. Puche‐Larrubia, Inmaculada C. Aranda‐Valera, Alejandro Escudero‐Contreras, Rosa Roldán‐Molina   +3 more
wiley   +1 more source

AGAPIR: A Novel PIWI‐Interacting RNA Enhancing Post‐Decompression Angiogenesis in Degenerative Cervical Myelopathy

Advanced Science, EarlyView.
The restoration of blood flow following surgical decompression for degenerative cervical myelopathy (DCM) significantly contributes to the amelioration of neurological deficits. This study identifies AGAPIR, an angiogenesis‐associated PIWI‐interacting RNA, enhances angiogenesis and motor function recovery post‐spinal cord decompression in a mouse model
Yongheng Xie, Yiling Peng, Tianyu Qin, Cuimei Chen, Zhenxiao Ren, Naibo Feng, Chungeng Liu, Songlin Peng, Houqing Long   +8 more
wiley   +1 more source

Fractures of the cervical spine

Clinics, 2013
OBJECTIVES: The aim of this study was to review the literature on cervical spine fractures. METHODS: The literature on the diagnosis, classification, and treatment of lower and upper cervical fractures and dislocations was reviewed.
Raphael Martus Marcon, Alexandre Fogaca Cristante, William Jacobsen Teixeira, Douglas Kenji Narasaki, Reginaldo Perilo Oliveira, Tarcisio Eloy Pessoa de Barros   +5 more
doaj   +1 more source