Results 71 to 80 of about 90,673 (283)

Airway management of patients with traumatic brain injury/C-spine injury [PDF]

Korean Journal of Anesthesiology, 2015
Traumatic brain injury (TBI) is usually combined with cervical spine (C-spine) injury. The possibility of C-spine injury is always considered when performing endotracheal intubation in these patients.
Jin Yong Jung
doaj   +1 more source

Microglial HVCN1 Deficiency Improves Movement and Survival of SOD1G93A ALS Mice by Enhancing Microglial Migration and Neuroprotection

Advanced Science, EarlyView.
Hydrogen voltage gated channel 1 (HVCN1) is upregulated in microglia of both ALS patients and its mouse model. HVCN1 deficiency enhances microglial migration via suppressing Akt signaling, promotes neurotrophic capacity and motor function, and prolongs survival of the SOD1G93A ALS mice. This study identifies HVCN1 as a novel, promising druggable target
Fan Wang, Ke‐Yu Zhang, Lang‐Jian Zhu, Wei‐Jue Li, Yang Wu, Xiang Gao, Xiao‐Ru Ma, Xiu‐Hua Yin, Jian‐Bin Wu, Xiao‐Kang Ye, Zhao‐Jun Dong, Di‐Xian Wang, Zhe Zhou, Shao‐Dong Wang, Lei Han, Zhi‐Nong Jiang, Jing‐Wei Zhao   +16 more
wiley   +1 more source

Prediction Score for Cervical Spine Fracture in Patients with Traumatic Neck Injury

Neurology Research International, 2021
Background. Cervical spine fracture is approximately 2%–5%. Diagnostic imaging in developing countries has several limitations. A computed tomography scan is not available 24 hours and not cost-effective.
Natsinee Athinartrattanapong, Chaiyaporn Yuksen, Sittichok Leela-amornsin, Chetsadakon Jenpanitpong, Sirote Wongwaisayawan, Pittavat Leelapattana   +5 more
doaj   +1 more source

Assessing the Relative Importance of Imaging and Serum Biomarkers in Capturing Disability, Cognitive Impairment, and Clinical Progression in Multiple Sclerosis

Advanced Science, EarlyView.
Using machine‐learning analyses in two independent multiple sclerosis cohorts, spinal cord atrophy and cortical degeneration emerged as key predictors of disability and progression independent of relapses. Deep gray matter damage further improved prediction, while serum biomarkers of brain damage provided complementary information, highlighting the ...
Alessandro Cagol, Pascal Benkert, Sabine Schaedelin, Mario Ocampo‐Pineda, Noemi Montobbio, Po‐Jui Lu, Batuhan Ayci, Antonia Wenger, Alfi Aran Shukur, Kornelius Kaim, Lester Melie‐Garcia, Matthias Weigel, Alessio Signori, Pasquale Calabrese, Ludwig Kappos, Maria Pia Sormani, Jens Kuhle, Cristina Granziera   +17 more
wiley   +1 more source

Engineered GM1 Intersects Between Mitochondrial and Synaptic Pathways to Ameliorate ALS Pathology

Advanced Science, EarlyView.
Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease driven by genetic and molecular disruptions affecting energy balance, protein homeostasis, and stress responses in nerve cells. Studies using human and rodent models identified convergent defects in mitochondria and synaptic function.
Federica Pilotto, Tristan Dellazizzo Toth, Silvano Bond, Alexander Schmitz, Rim Diab, Sara Y. Ngo Tenlep, Brian Mooney, Silvia Erni, Martina Schobesberger, Olivier Scheidegger, Camille Peitsch, Smita Saxena   +11 more
wiley   +1 more source

Impact of intravenous acetaminophen therapy on the necessity of cervical spine imaging in patients with cervical spine trauma

Chinese Journal of Traumatology, 2014
【Abstract】Objective: We evaluated a new hypothesis of acetaminophen therapy to reduce the necessity of imaging in patients with probable traumatic cervical spine injury. Methods:Patients with acute blunt trauma to the neck and just posterior midline
Ahmadi Koorosh, Hashemian Amir Masoud, Pishbin Elham, Sharif-Alhoseini Mahdi, Rahimi-Movaghar Vafa   +4 more
doaj  

Traumatic Death due to Simultaneous Double Spine Fractures in Patient with Ankylosing Spondylitis

Case Reports in Orthopedics, 2015
The aim of this study is to report the rare occurrence of simultaneous double spine fractures in a patient with progressive ankylosing spondylitis (AS). An 82-year-old male with established AS had low-energy falls.
Mitsuru Yagi, Shunsuke Sato, Atsushi Miyake, Takashi Asazuma   +3 more
doaj   +1 more source

Five cases of paediatric cervical spine distraction injury

South African Journal of Radiology, 2000
Cervical spine distraction injury was considered rare in children, but current literature claims that atlanto-occipital distraction is a major contributor to paediatric trauma mortality.
S. Andronikou, S. Dix-Peek, D. Meerkotter   +2 more
doaj   +1 more source

Acute traumatic unilateral cervical C4–C5 facet dislocation in pediatric toddlers

BMC Musculoskeletal Disorders, 2020
Background The present study is to highlight the challenges in managing cervical spine injuries in toddlers (less than 4 years of age) without neurological deficit. Cases of unilateral cervical C4–C5 facet dislocation in toddlers are very rare.
Wongthawat Liawrungrueang, Rattanaporn Chamnan, Weera Chaiyamongkol, Piyawat Bintachitt   +3 more
doaj   +1 more source

Diffusion Tensor Imaging in a Large Longitudinal Series of Patients With Cervical Spondylotic Myelopathy Correlated With Long-Term Functional Outcome [PDF]

, 2018
BACKGROUND Fractional anisotropy (FA) of the high cervical cord correlates with upper limb function in acute cervical cord injury. We investigated the correlation between preoperative FA at the level of maximal compression and functional recovery in a ...
Budde, Matthew D., Kaushal, Mayank, Kurpad, Shekar N., Motovylyak, Olesya, Rao, Avinash, Schmit, Brian D., Soliman, Hesham, Vedantam, Aditya, Wang, Marjorie C.   +8 more
core   +1 more source