Molecular Oncology, EarlyView.Comprehensive analysis of genomic mutations, gene expression, DNA methylation, and pathway analysis of TCGA data was carried out to define cancer types in which proteasome subunits expression is associated with worse survival. Albeit the effect of specific proteasome subunits on cellular function, the main role of the proteasome is better evaluated ...
Ruba Al‐Abdulla +5 more
wiley +1 more source
AI in Cervical Cancer Cytology Diagnostics: A Narrative Review of Cutting-Edge Studies
BioengineeringBackground: The integration of artificial intelligence (AI) into cervical cancer diagnostics has shown promising advancements in recent years. AI technologies, particularly in the analysis of cytological images, offer potential improvements in diagnostic
Daniele Giansanti +5 more
doaj +1 more source
Non-Hodgkin’s Lymphoma of the Uterine Cervix [PDF]
, 2012 Non Hodgkin’s Lymphoma (NHL) causes many deaths worldwide and its incidence is increasing. They occur commonly in middle aged and elderly people and are disseminated at diagnosis.
Kaler, AK, Vasudev, DS
core
Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma
Molecular Oncology, EarlyView.The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias +12 more
wiley +1 more source
Pathology of the cervix during pregnancy: screening and treatment strategy (the review) [PDF]
Гинекология, 2016 The review presents the current state of pathological conditions of the cervix. The changes of the cervix during pregnancy, the risk of cervical pathology with pregnant women are described here. The modern classification of pathological conditions of the
T V Pikuza +4 more
doaj
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Clinical characteristics and pathogenesis of rapid and precipitous labor in women [PDF]
Гинекология, 2014 Article presents retrospective-prospective analysis of pregnancy course and outcomes of rapid and precipitous labor in 115 women with term pregnancies. Morphological and immunohistochemical characterics of the cervix were studied.
M E Gelezova, L I Malceva, T P Zephirova
doaj
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
Human Pappilomavirus Genotype in Cervical Tissue of Patients with Cervical Intraepithelial Neoplasia (CIN) 1, CIN 2, and CIN 3 [PDF]
, 2016 Objectives: to determine the genotype of HPV in patients with precancerous lesions of cervical tissue.Materials and Methods: An observational study with cross sectional study of patients paraffin block CIN1, CIN2, CIN3 was conducted in Dr Soetomo ...
Alia, R. (Rahmi) +4 more
core +1 more source
Dosimetric comparison study between intensity modulated radiation therapy and three-dimensional conformal proton therapy for pelvic bone marrow sparing in the treatment of cervical cancer. [PDF]
, 2010 The objective was to compare intensity-modulated radiation therapy (IMRT) with 3D conformal proton therapy (3DCPT) in the treatment of cervical cancer. In particular, each technique's ability to spare pelvic bone marrow (PBM) was of primary interest in ...
Huh, Soon N +7 more
core +2 more sources