Results 131 to 140 of about 117,385 (313)

Interactions of Antibody Drug Conjugate Anti‐Tubulin and Topoisomerase I Inhibitor Payloads with Radiotherapy to Potentiate Immunotherapy

open access: yesAdvanced Science, EarlyView.
Antibody drug conjugates deliver their cytotoxic anti‐tubulin or topoisomerase I inhibitor payloads to tumors through cancer cell receptor targeting. The released drug payloads induce cellular changes that interact with radiotherapy resulting in radiosensitization that improves cancer cell kill and stimulates anti‐tumor immune responses.
Jacqueline Lesperance   +17 more
wiley   +1 more source

History of Cervical Cancer and the Role of the Human Papillomavirus, 1960-2000

open access: yes, 2009
Annotated and edited transcript of a Witness Seminar held on 13 May 2008. Introduction by Professor Anne M Johnson, Division of Population Health and Institute for Global Health, UCL.
Reynolds, LA, Tansey, EM
core  

Dysuria following hysterectomy

open access: yes, 1957
In the observations of the pelvic nerves both in the reconstruction model of the pelvis of newborn and that of the extripated specimen after OKABAYASHI's hysterectomy as well as in the observations of pelvic nerves at autopsy, it has been verified that ...
Saratani, Kazuo
core   +1 more source

Causal role of immune cells on cervical cancer onset revealed by two-sample Mendelian randomization study

open access: yesScientific Reports
Cervical cancer (CC) is a prevalent gynecological cancer worldwide that significantly impacts the quality of life and the physical and mental well-being of women. However, there have been limited studies utilizing Mendelian randomization (MR) analysis to
Zicheng Zhao   +6 more
doaj   +1 more source

Point-A vs. volume-based brachytherapy for the treatment of cervix cancer: A meta-analysis. [PDF]

open access: yesRadiother Oncol, 2022
Hande V   +8 more
europepmc   +1 more source

LMO7 Suppresses Tumor‐Associated Macrophage Phagocytosis of Tumor Cells Through Degradation of LRP1

open access: yesAdvanced Science, EarlyView.
LMO7 in tumor‐associated macrophages suppresses phagocytosis of tumor cells and limits cytotoxic T lymphocytes infiltration, fostering tumor progression. Mechanistically, LMO7 mediates the ubiquitination and degradation of the phagocytic receptor LRP1, impairing its ability to engulf tumor cells and driving macrophages toward an antitumor phenotype ...
Mengkai Li   +12 more
wiley   +1 more source

CDK4/6 Inhibition Induces CD8+ T Cell Antitumor Immunity via MIF‐Induced Functional Orchestration of Tumor‐Associated Macrophages

open access: yesAdvanced Science, EarlyView.
CDK4/6 inhibition promotes CD8+ T cell expansion through tumor‐macrophage crosstalk by activating HIF‐1α and enhancing MIF‐CD44/CD74 signaling. This reprograms TAMs to boost MHC‐I antigen presentation, and CDK4/6 inhibitor‐trained M1 TAM supernatant therapy synergizes with low‐dose PD‐1 blockade to restore antitumor immunity.
Lin He   +17 more
wiley   +1 more source

Cervix Cancer in Sub-Saharan Africa: An Assessment of Cervical Cancer Management. [PDF]

open access: yesJCO Glob Oncol, 2021
Burt LM   +14 more
europepmc   +1 more source

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