Results 171 to 180 of about 117,385 (313)

HNRNPD Induces Radioresistance in Nasopharyngeal Carcinoma by Sequestering GRAMD4 mRNA in Stress Granules

open access: yesAdvanced Science, EarlyView.
HNRNPD promotes radioresistance in nasopharyngeal carcinoma by enhancing stress granule assembly and sequestering GRAMD4 mRNA. This suppresses GRAMD4 translation and inhibits mitochondrial apoptosis. Targeting the integrated stress response with ISRIB restores GRAMD4 expression and sensitizes tumors to radiotherapy, revealing a translational control ...
Yingzi Li   +13 more
wiley   +1 more source

Neoadjuvant chemotherapy for locally advanced cervix cancer

open access: yes, 1999
Cervix cancer meta-analysis collabo
core   +1 more source

Comparison of apparent diffusion coefficient maps to T2-weighted images for target delineation in cervix cancer brachytherapy

open access: yes, 2011
Purpose: T2-weighted (T2W) magnetic resonance imaging (MRI) has been used for target delineation in cervix cancerbrachytherapy. The objective of this study was to examine the feasibility of using diffusion-weighted magnetic resonanceimaging (DWI) for ...
Vamsidhar R. Narra   +4 more
core  

Knowledge about cervical cancer, human papilloma virus and attitude towards acceptance of vaccination among female students

open access: yesPayesh, 2015
Objective (s): Human papilloma virus (HPV) is a leading cause of cervical cancer and sexually transmitted infections are common health problems among young females.
Delara salehifar   +2 more
doaj  

Cuproptosis and Mitophagy Mediated by the THUMPD1/IGF2R‐Dependent Suppression of AKT and Activation of AMPK Signaling Suppress Lung Adenocarcinoma Progression

open access: yesAdvanced Science, EarlyView.
THUMPD1 drives a tumor‐suppressive signaling cascade in lung adenocarcinoma by promoting IGF2R expression. IGF2R associates with PPP2R1A to suppress AKT and activate AMPK, leading to SLC31A1 upregulation and copper accumulation. Elevated copper disrupts mitochondrial metabolism and induces excessive mitophagy, thereby restraining tumor growth and ...
Kai Wu   +10 more
wiley   +1 more source

Effect of p21Waf1 and p27Kip1 on centrosome replication and proliferation of breast cancer cell

open access: yes, 2010
Aberrant centrosome numbers are detected in virtually all cancers,increasing the risk for cell division errors and chromosomal instability.
Yin-Lin Ge   +5 more
core  

Designing theranostic radiopharmaceutical trials for uterine cervix cancer. [PDF]

open access: yesFront Oncol
Fabian D   +5 more
europepmc   +1 more source

β‐Elemene Rescues Radiation‐Induced Enteritis by Orchestrating a Host‐Microbiome Circuit That Fuels Epigenetic DNA Repair

open access: yesAdvanced Science, EarlyView.
This study elucidates that β‐elemene promotes cellular uptake of L. gasseri‐derived lactate by enhancing the membrane translocation of MCT1 in a CD147‐dependent manner. Intracellular lactate, through the lactylation of RBBP4 at the K26 site, recruits EP300 to the promoter regions of downstream genes (POLD1/POLD3), catalyzing H3K27ac modification.
Jiancheng He   +10 more
wiley   +1 more source

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