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Maximally selected chi-square statistics and binary splits of nominal variables [PDF]
We address the problem of maximally selected chi-square statistics in the case of a binary Y variable and a nominal X variable with several categories. The distribution of the maximally selected chi-square statistic has already been derived when the best
Boulesteix, Anne-Laure
core +3 more sources
MGM as a Large‐Scale Pretrained Foundation Model for Microbiome Analyses in Diverse Contexts
We present the Microbial General Model (MGM), a transformer‐based foundation model pretrained on over 260,000 microbiome samples. MGM learns contextualized microbial representations via self‐supervised language modeling, enabling robust transfer learning, cross‐regional generalization, keystone taxa discovery, and prompt‐guided generation of realistic,
Haohong Zhang +5 more
wiley +1 more source
Coronavirus disease 2019 (COVID-19) outbreak was first reported in Wuhan, and its manifestations in pregnancy can be variable ranging from mild illness to severe acute respiratory syndrome.
Bhanupreet Kaur +3 more
doaj +1 more source
In trophoblast cells, T/S (TNFα + SM164) activated caspase‐3, which cleaved GSDME to switch apoptosis to pyroptosis, causing cell swelling, membrane rupture, and release of LDH, HMGB1, IL‐1β and IL‐18. These cytokines induced pro‐inflammatory macrophage polarization, which in turn reinforced pyroptotic signaling in trophoblasts, amplifying systemic ...
Baoying Huang +15 more
wiley +1 more source
Background and Aims Although some women who undergo cesarean section need to receive prophylactic Enoxaparin due to the increased risk of thromboembolism during their puerperium period, the question is always raised of whether this drug with the ...
Leili Hafizi +3 more
doaj +1 more source
PA accumulates after hypoxic‐ischemic injury and stabilizes the E3 ligase TRIM59 in OPCs. Stabilized TRIM59 enhances ubiquitination and degradation of Olig2, blocking differentiation and causing hypomyelination in PWMI. Modulating PA synthesis restores Olig2 levels, improves myelination, and ameliorates behavioral deficits, defining a metabolically ...
Xinyu Li +8 more
wiley +1 more source
Extremely Preterm Cesarean Delivery “En Caul”
Objective: Intact amniotic membranes may serve to protect the extremely fragile preterm infant from some of the mechanical forces caused by strong uterine contraction.
Chia-Hui Lin +6 more
doaj +1 more source
BACKGROUND: Induction of labor among low-risk, 39-week nulliparas increased significantly in the United States following publication of the outcomes of A Randomized Trial of Induction Versus Expectant Management trial.
Andrea T. Jelks, MD +2 more
doaj +1 more source
Unlike deceased‐donor liver transplantation, living‐donor liver transplantation (LDLT) for Budd‐Chiari Syndrome (BCS) presents distinctive challenges in hepatic venous (HV)‐outflow reconstruction because diseased HV–inferior vena cava (IVC) cannot be entirely replaced with healthy donor vessels.
Koichiro Hata +4 more
wiley +1 more source

