Results 61 to 70 of about 149,101 (296)

Labor Epidural Analgesia and Autism Spectrum Disorder in Offspring: A Population‐Based Case–Control Study

open access: yesAutism Research, EarlyView.
ABSTRACT While the immediate benefits of labor epidural analgesia (LEA) are well established, recent studies have raised concerns about possible associations with autism spectrum disorder (ASD). Therefore, we examined the association between LEA and ASD in offspring.
Taniqua T. Ingol   +7 more
wiley   +1 more source

Prevalence of Repeat Cesarean Section in a Tertiary Care Hospital

open access: yesJournal of Nepal Medical Association, 2020
Introduction: Cesarean section is the surgical delivery of a baby through an incision made in the mother's abdomen and uterus. Repeat cesarean section has recently increased, partly because of concern about increased risk of uterine rupture in women ...
Jyotshna Sharma   +3 more
doaj   +1 more source

Tacrolimus exposure during pregnancy in kidney and liver transplantation recipients: A comparison between whole blood and plasma concentration‐to‐dose ratios

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Tacrolimus monitoring is generally performed in whole blood (WB). Most (>85%) of circulating tacrolimus is bound to red blood cells. During pregnancy, WB monitoring might be suboptimal because of physiological changes including increased plasma volume and decreased haematocrit.
Jildau R. Meinderts   +7 more
wiley   +1 more source

Using linked data to explore medical complications associated with Robson classification of cesarean deliveries in Massachusetts, 2011 to 2018AJOG Global Reports at a Glance

open access: yesAJOG Global Reports
Background: Cesarean delivery rates in the United States far exceed the World Health Organization (WHO)’s recommended population cesarean rate of 15%. This has resulted in calls from experts to reduce cesarean delivery rates.
Ruby Barnard-Mayers, MPH   +4 more
doaj   +1 more source

Perinatal Outcome of Vaginal Breech Delivery versus Caesarean Breech Delivery in a Tertiary Care Center

open access: yesJournal of Nepal Medical Association, 2018
Introduction: Breech delivery has always been matter of interest in obstetrics. Cesarean breech delivery has been preferred method of delivery. We aim to find out any differences in outcome between vaginal breech delivery and cesarean breech delivery in ...
Rajendra Kumar Chaudhary   +2 more
doaj   +1 more source

Therapeutic drug monitoring of antimicrobials in a paediatric setting: A retrospective single‐centre study

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Paediatric pharmacokinetics differ significantly from adults due to age‐related physiological changes, necessitating precise dose adjustments. However, data on therapeutic drug monitoring (TDM) implementation in paediatric setting remain limited.
Gianluca Gazzaniga   +20 more
wiley   +1 more source

Physiologically‐based pharmacokinetic modelling of uridine 5′‐diphosphoglucorosultransferase (UGT) substrate drugs in pregnant women

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims While pregnancy‐related changes in phase I enzyme activity are well‐documented, less is known about the impact on phase II enzymes. This study aimed to test the hypothesis that changes in the pharmacokinetics (PK) of uridine 5′‐diphosphoglucuronosyltransferase (UGT) substrates during pregnancy result from altered enzyme expression or activity ...
William Saffaf   +6 more
wiley   +1 more source

Detecting Rates, Trends and Determinants of Cesarean Section Deliveries in Iran Using Generalized Additive Mixed Models

open access: yesEpidemiology, Biostatistics and Public Health, 2022
Background: The present study aimed to investigate the trend of cesarean section and its related factors through the recent years. Methods: The study data containing delivery information from Hamadan hospitals and are recorded from 2001 to 2014 ...
Marzieh Mahmoodi   +3 more
doaj  

Caesarean section and risk of unexplained stillbirth in subsequent pregnancy [PDF]

open access: yes, 2003
Background Caesarean section is associated with an increased risk of disorders of placentation in subsequent pregnancies, but effects on the rate of antepartum stillbirth are unknown.
Alfirevic   +36 more
core   +1 more source

Humans are not unique: difficult birth is common in placental mammals

open access: yesBiological Reviews, EarlyView.
ABSTRACT Human childbirth is widely presumed to be uniquely difficult and dangerous compared to birth in other mammals. Tight fetopelvic proportions can result in obstructed labour and contribute to high rates of maternal and neonatal mortality. Ideas summarised under the ‘obstetrical dilemma’ have contributed to this assumption by explaining difficult
Nicole D. S. Grunstra
wiley   +1 more source

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