Increasing Lipid Nanoparticle mRNA Copy Number Improves Transfection Potency
As lipid nanoparticle (LNP) systems are the leading platform for in vivo nucleic acid delivery, improving transfection potency of these systems is of considerable interest. In this work, we explored a post‐mixing formulation method involving a two‐step buffer exchange that increased the number of mRNA copies within each LNP while reducing the number of
Yao Zhang +12 more
wiley +1 more source
Multi-Level Physiological and Metabolomic Responses of <i>Hypnum plumaeforme</i> Reveal Oxidative Imbalance, Photosynthetic Disruption and Metabolic Reprogramming Under Cesium Stress. [PDF]
Sun S +7 more
europepmc +1 more source
Strong Fully Reprocessable Engineered Wood Composites
Engineering a hyperbranched adhesive with complementary imine‐bond and hydrogen‐bond networks, combining it with wood particles to fabricate the wood composite (WP/HTP) under mild hot‐pressing conditions. The WP/HTP exhibits 100% mechanical strength recovery after three cycles of reprocessing, and the reprocessed modulus of rupture (MOR) and modulus of
Xilin Zhang +9 more
wiley +1 more source
Association of eight urinary metals and trouble sleeping: A cross-sectional study. [PDF]
Ma Q +7 more
europepmc +1 more source
Ionic cocrystal‐programmed ionic organization establishes a general strategy for electrostatic programming in polymeric photocatalysts. ABSTRACT Controlling the spatial organization of ions in polymeric photocatalysts remains a fundamental challenge for optimizing charge transport and catalytic selectivity in solar‐driven hydrogen peroxide (H2O2 ...
Anna Lo Presti +6 more
wiley +1 more source
High-Sensitivity Cesium Aerosol Sensing for Nuclear Severe-Accident Monitoring by Integrating Laser-Induced Plasma RGB Imaging with Convolutional Neural Network (CNN) Analysis. [PDF]
Choi SU, Koo CU.
europepmc +1 more source
Alternating oxidative–reductive pulses synchronize CO2‐derived *CO and NH3‐derived *NHx intermediates over dual Cu and Co single‐atom sites, enabling urea and ethyl urea formation with a total C─N Faradaic efficiency of 42 ± 4%. In situ spectroscopy and theoretical calculations elucidate complementary Cu and Co functions, while oxidative controls ...
Putri Ramadhany +8 more
wiley +1 more source
Geopolymer-Assisted Conversion of Cs-Exchanged 13X Zeolite into Stable Cs-Aluminosilicates for Long-Term Cesium Immobilization. [PDF]
Omerašević M +6 more
europepmc +1 more source
Biomass DNA: An Emerging Building Block for Advanced Materials
Biomass DNA is rapidly emerging from its traditional role as a genetic blueprint to serve as a versatile abundant, highly programmable polymeric building block. This review highlights the transformation of macroscopic bulk biomass DNA into next generation of functional materials, spanning from dynamic hydrogels, sustainable bioplastics, and high ...
Yuwei Hu, Itamar Willner, Li Niu
wiley +1 more source
Vitamin C‐Induced Photo‐Redox Threshold Enables High‐Fidelity Volumetric Printing of Collagen
Tomographic volumetric printing (TVP) of native proteins is limited by uncontrolled background crosslinking. Here, vitamin C is introduced as a biocompatible redox regulator to establish a tunable nonlinear polymerization threshold response for TVP.
Bin Wang +5 more
wiley +1 more source

