Results 31 to 40 of about 35,600 (259)

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Drinking high-energy electrolytic water decreases internal radiation exposure caused by the Fukushima Daiichi Nuclear power plant disaster [PDF]

Nuclear Technology and Radiation Protection, 2016
The Fukushima Daiichi Nuclear Power Plant disaster on March 11, 2011, caused radiation hazards throughout Fukushima Prefecture. Cesium was absorbed by soil and plants and transferred to livestock.
Sawajiri Masahiko, Miyamoto Shoichi, Yamanouchi Kohkoh, Wada Shoji, Srimawong Preeyaporn, Nomura Yuji, Uchida Takashi   +6 more
doaj   +1 more source

A High-Sensitivity Cesium Atomic Magnetometer Based on A Cesium Spectral Lamp

Applied Sciences, 2023
Based on a low-noise cesium spectral lamp, a high-sensitivity self-oscillating cesium atomic magnetometer with a wide operating temperature range has been developed, solving problems with existing sensors such as a limited operating temperature range and
Yuan-Tian Lu, Lei-Song Liu, Yong-Qi Shi, Tian Zhao, Wan-Hua Zhu, Tie-Fu Zhang, Wu-Ming Liu, Xiao-Juan Zhang   +7 more
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Cesium hydrogen tartrate and anomalous dispersion of cesium [PDF]

Acta Crystallographica Section A, 1978
Cesium hydrogen (+)-tartrate is orthorhombic, P212121, a = 8.076 (3), b = 11.621 (5), c = 7.692 (3) A, Z = 4, Dx = 2.594 g cm-3, at 22°C. Its structure, nearly the same as that of ammonium hydrogen tartrate, was refined to R = 0.016 for 2442 reflections (F2 > 3σ) out to d = 0.66 A.
L. K. Templeton, D. H. Templeton
openaire   +1 more source

Additional contamination of shiitake mushrooms (Lentinula edodes) cultivated on bed-logs in an artificial environment

Journal of Wood Science
Radioactive cesium was released into the environment from the Fukushima Daiichi Nuclear Power Plant of Tokyo Electric Power Company, which was damaged by the Great East Japan Earthquake. The shiitake industry suffered various damages as a result.
Masakazu Hiraide, Eriko Sugimoto, Yoshinori Imai, Yoichi Ishikawa   +3 more
doaj   +1 more source

Room-temperature adsorption behavior of cesium onto calcium silicate insulation

Mechanical Engineering Journal, 2020
A calcium silicate insulator material was investigated for its interaction with non-radioactive cesium at room temperature by batch-type adsorption experiments. An industrial-grade calcium silicate was weighted and ground into powder with an average size
Muhammad RIZAAL, Takumi SAITO, Koji OKAMOTO, Nejdet ERKAN, Kunihisa NAKAJIMA, Masahiko OSAKA   +5 more
doaj   +1 more source

Study of cesium sorption by a Brazilian bentonite

Brazilian Journal of Radiation Sciences, 2021
Engineered and natural barriers compose the disposal system of near surface repository to store low and intermediate level radioactive wastes. Waterproofing barriers are constituted of clays, such as the bentonite, in order to avoid or to limit the ...
Daisy Mary Marchezini dos Santos, Clédola Cássia Oliveira de Tello   +1 more
doaj   +1 more source