Results 201 to 210 of about 412,675 (264)

Comparative Effectiveness of Cytisinicline and Varenicline for Smoking Cessation: A Matching-Adjusted Indirect Comparison (MAIC). [PDF]

J Health Econ Outcomes Res
Rubinstein M, Rowe D, Perdok R, Jacobs C.   +3 more
europepmc   +1 more source

A Brain‐Penetrant Nanobody Reveals GSK3β‐Driven Proline‐Directed Phosphorylation as a Master Regulator of Ischemic Neurodegeneration

Advanced Science, EarlyView.
A brain‐targeted nanoparticle enables delivery of a therapeutic nanobody (Nb.29E9) that inhibits pathogenic GSK3β signaling. This intervention restores AMPK/mTORC1/TGFβ homeostasis, attenuates neuroinflammation and oxidative stress, and promotes long‐term functional recovery after ischemic stroke.
Lan Li, Muyang Li, Lei Sun, Ying Yang, Yuanshun Wu, Ziyi Yin, Anni Wang, Peiyang Zhou, Shaoxiang Luo, Jian Chen, Jun Qin, Zhibing Ai, Zilong Yuan, Zhiqiang Dong, Min Zhang   +14 more
wiley   +1 more source

Non-Contact Detection of Apnea-like Breathing Cessations Using Laser Speckle Pattern Analysis. [PDF]

Sensors (Basel)
Dutta A, Shemer A, Schwarz A, Danan Y, Beiderman Y.   +4 more
europepmc   +1 more source

Smoking cessation: development smoking cessation intervention

Report on barriers and facilitators for participating in lung cancer screening, receiving personal health information and smoking cessation.
openaire   +1 more source

Beyond Molecular Determinism: State‐Convergent Polymerization as a Functional Design Principle Under Chemical Complexity

Advanced Science, EarlyView.
This work introduces state‐convergent polymerization (SCP), a polymerization framework in which chemically diverse reaction pathways converge toward a reproducible functional polymeric state rather than a defined molecular structure. Using melanin and polydopamine as exemplars, SCP explains how robust polymer functions emerge under chemical and ...
Seonki Hong
wiley   +1 more source

Delivery of a one-week chewing gum for promoting smoking cessation: A pilot randomized controlled trial. [PDF]

Tob Induc Dis
Li MY, Yiu YT, Zhao SZ, Cheung YTD, Deng K, Lam TH, Wang MP.   +6 more
europepmc   +1 more source

Intrinsically Mitochondria‐Targeting Nanozyme via Coordination‐Assembly of Natural Quercetin for Cascade Antioxidant Therapy of Cerebral Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
This study uncovers that quercetin naturally targets mitochondria. By coordinating quercetin with Fe3+, we engineer an ultrasmall cascade nanozyme (MCN) with superoxide dismutase‐catalase activities. MCN crosses the damaged blood–brain barrier, scavenges mitochondrial ROS, prevents mitochondrial DNA leakage, and blocks the cGAS‐STING pathway, thereby ...
Wenxuan Zheng, Zhicheng Wang, Xin Zhou, Shuya Wang, Xiaojing Shi, Tingli Xiong, Ruishi Li, Yuting Lin, Zhen Chen, Jiawen Wei, Fei Li, Jinwen Ge, Kelong Ai, Chong Liu, Guiming Deng   +14 more
wiley   +1 more source

ChatGPT-4's Consistency, Specificity, and Inclusion of Behavior Change Techniques in Delivering Smoking Cessation Advice in Traditional Chinese: A Content Analysis. [PDF]

Nicotine Tob Res
Xie XY, Zhang MJ, Cheung ZJK, Luk TT, Wang MP, Lam TH, Cheung YTD.   +6 more
europepmc   +1 more source

Surfaceome Reprogramming of Stemsomes Promotes Lung Cancer Targeting via Potentiated Receptor–Ligand Interactions

Advanced Science, EarlyView.
This study presents a surfaceome‐reprogramming strategy for mutation‐independent lung cancer therapy by repurposing dexamethasone to prime mesenchymal stem cell‐derived nanovesicles. The engineered vesicles leverage multi‐valent interactions mediated by upregulated adhesion proteins, EPHA2, and NOTCH3.
Geunhye Kim, In Ah Kwon, Bo Seop Jeong, Hyo Seon Kim, Joo‐Hwan Park, Sung Jean Park, Sang‐Rae Lee, Youngki Lee, Dongwoo Khang   +8 more
wiley   +1 more source

Mobile App-Based Smoking Cessation in Hispanic or Latino Adults: Culturally Tailored Spanish-Language Formative App Development Study. [PDF]

JMIR Form Res
Martinez U, Vinci C, Hernandez P, Horta M, Blackwell R, Brandon TH, Simmons VN.   +6 more
europepmc   +1 more source