Results 101 to 110 of about 12,628 (230)

Pain trajectories in children and adolescents with cerebral palsy: A longitudinal population‐based register study

open access: yesDevelopmental Medicine &Child Neurology, EarlyView.
Four pain trajectories were identified in a population‐based register study of 4887 children and adolescents with cerebral palsy: (1) increasing trend, low probability of experiencing pain (20.28%), (2) increasing trend, high probability of experiencing pain (30.30%), (3) decreasing trend (26.85%), and (4) consistently high probability of experiencing ...
May Phyu Sin   +3 more
wiley   +1 more source

CFC syndrome [PDF]

open access: yesAmerican Journal of Medical Genetics Part A, 2002
Giovanni Neri   +3 more
openaire   +1 more source

Safety strategies for everyday community physical activity by adults with cerebral palsy and high support needs: A qualitative case series

open access: yesDevelopmental Medicine &Child Neurology, EarlyView.
Safety strategies used by adults with complex forms of cerebral palsy when participating in community‐based physical activity were explored in this study. Physical assistance was the main safety strategy in use, provided for four key purposes. The attributes of support people in community settings was key to experiences of safety.
Georgia B McKenzie   +6 more
wiley   +1 more source

World Health Organization Healthy Ageing model applied to adults with cerebral palsy: A systematic review of reported intrinsic capacity measures

open access: yesDevelopmental Medicine &Child Neurology, EarlyView.
This systematic review reports on quantitative measures of intrinsic capacity domains of the WHO Healthy Ageing model for adults with CP. Reports from 102 studies showed reduced locomotor, vitality andn possibly cognitive intrinsic capacity reserves for adults aged 30–45 years.
Woroud Alzaher   +4 more
wiley   +1 more source

FVIIIa Mimetics: New Approaches and Next‐Generation Initiatives

open access: yesHaemophilia, EarlyView.
ABSTRACT Emicizumab has revolutionized hemophilia A care, yet limitations regarding the “ceiling” of hemostatic efficacy (equivalent to mild hemophilia) and global access persist. This review critically examines two distinct paradigms shaping the future of care: Innovation and Access. Regarding innovation, we synthesize the latest clinical data on next‐
Tadashi Matsushita   +2 more
wiley   +1 more source

An Ex Vivo Pharmacodynamic Study of KN057, a Tissue Factor Pathway Inhibitor Neutralizing Antibody, in Plasma Samples From Patients With Haemophilia or VWD3

open access: yesHaemophilia, EarlyView.
ABSTRACT Introduction Tissue factor pathway inhibitor (TFPI), a key regulator of tissue factor‐initiated coagulation through FXa‐dependent inhibition of the tissue factor‐FVIIa complex, has emerged as a promising target for restoring thrombin generation.
Mankai Ju   +5 more
wiley   +1 more source

Mortality trends for diabetes mellitus, hypertension and cardiovascular disease among people living with and without HIV in Brazil during the COVID‐19 pandemic, 2020–2022

open access: yesHIV Medicine, EarlyView.
Abstract Introduction People living with HIV (PLWH) face an increasing burden of non‐AIDS‐related chronic conditions. However, how the COVID‐19 pandemic affected chronic disease‐related mortality in this population remains unclear. We assessed changes in mortality among PLWH in Brazil during the COVID‐19 pandemic.
Tatyellen Natasha da Costa Oliveira   +7 more
wiley   +1 more source

Tissue Resident Memory Cells: Friend or Foe?

open access: yesImmunology, EarlyView.
Tissue‐resident memory T cells (TRM cells) are specialised immune cells in barrier tissues like the lungs, skin and gut, providing rapid host defence and tumour surveillance. Their retention and differentiation are regulated by molecules such as CD69, CD103 and TGF‐β. Dysregulation of TRM cells can lead to chronic activation, driving conditions such as
Chidimma F. Chude   +2 more
wiley   +1 more source

Thinking and Talking About War: How the Public in Six Countries Discusses the Outbreak of the War in Ukraine

open access: yesJCMS: Journal of Common Market Studies, EarlyView.
Abstract The Russian aggression in Ukraine, launched on 24 February 2022, marked the return of conventional war in the European continent. While Western leaders have framed the ongoing conflict through a common narrative when speaking internationally, which varies in its national nuances, much less is known about the images and lenses that the European
Carlotta Mingardi   +2 more
wiley   +1 more source

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