Results 61 to 70 of about 1,722,483 (221)

Single‐Cell Dissection of Therapy‐Induced Remodeling Uncovers a Fibroblast‐Driven Immunosuppressive Niche and Targetable Vulnerabilities in Lethal Prostate Cancer

open access: yesAdvanced Science, EarlyView.
Single‐cell longitudinal profiling reveals that androgen‐deprivation therapy induces a DPT+ fibroblast‐complement axis that suppresses macrophage inflammation and drives CD8+ T cell exhaustion in prostate cancer. Concurrently, resistant epithelial subpopulations persist and engage TSPAN1‐ and NRXN1‐mediated programs promoting CRPC and neuroendocrine ...
Yang Chen   +19 more
wiley   +1 more source

A CFD-DEM-FEM framework for sediment-laden free-surface flow interacting with flexible structures

open access: yesEngineering Applications of Computational Fluid Mechanics
Coastal and offshore protective structures are often loaded by free-surface flows that carry sediment. This study develops a three-phase numerical framework that couples Computational Fluid Dynamics (CFD), the Discrete Element Method (DEM), and the ...
Zhuolin Su   +4 more
doaj   +1 more source

Characterising vertical plug flow pneumatic conveying using CFD-DEM

open access: yes
OpenFOAM and Aspherix simulation data for the paper, "Characterising vertical plug flow pneumatic conveying using CFD-DEM". It contains the full simulation data of the "base case", which corresponds to Section 4.1 of the paper.
Erken, Oguzhan   +2 more
core   +1 more source

Single‐Cell Transcriptomic Analysis of Tumor Heterogeneity and the Microenvironment in Pseudomyxoma Peritonei

open access: yesAdvanced Science, EarlyView.
This study presents a single‐cell atlas of pseudomyxoma peritonei spanning primary and paired metastatic lesions. Distinct epithelial substates, stromal remodeling, immune exclusion, lipid metabolic reprogramming, and a candidate angiogenic network were identified in metastatic lesions.
Xi Li   +14 more
wiley   +1 more source

On charge percolation in slurry electrodes used in vanadium redox flow batteries

open access: yesElectrochemistry Communications, 2019
In vanadium redox flow battery systems porous carbon felts are commonly employed as electrodes inside the flow channel. Recently, slurry electrodes (or flow suspension electrodes) were introduced as a potentially viable electrode system.
Johannes Lohaus   +4 more
doaj   +1 more source

Sustainable Fabrication of Tailored Bone Substitutes: From High‐Throughput Scaffold Manufacturing, Scaled‐Up HMSC Expansion to Dynamic Cultivation in a Perfusion Bioreactor

open access: yesAdvanced Science, EarlyView.
ABSTRACT The demand for off‐the‐shelf biocompatible bone substitutes has driven the development of numerous independent in vitro technologies to generate products resembling physiological tissues. Due to technical challenges and overly simplified cultivation approaches/niches, the end‐products are often uniformly shaped and inferior to native bone ...
Franziska Braun   +10 more
wiley   +1 more source

Dynamic thermal modelling using CFD [PDF]

open access: yes, 2003
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.Buildings expend vast quantities of energy, which has a detrimental impact on the environment.
Somarathne, Shini
core   +5 more sources

Datasets for the article: Simulation of Microcapsule Transport in Fractured Media Using Coupled CFD-DEM

open access: yes
In our paper 'Simulation of Microcapsule Transport in Fractured Media Using Coupled CFD-DEM', we employed the coupled computational fluid dynamics and discrete element method (CFD-DEM) to simulate the transport of microcapsules under various scenarios ...
Xiaoming Zhang (17904650)
core   +1 more source

Polymorphic Superparaelectric Engineering Boosting Energy Storage Capacity in BaTiO3‐Based Ceramics

open access: yesAdvanced Science, EarlyView.
Herein, Ca2+ incorporation promotes the coexistence of CaTiO3‐/BaTiO3‐derived paraferroelectric states, stabilizing cubic‐orthorhombic‐tetragonal polymorphic superparaelectric phases. This minimizes polarization energy barriers, facilitating full polarization saturation without compromising efficiency.
Pan Liu   +9 more
wiley   +1 more source

PyGran: An object-oriented library for DEM simulation and analysis

open access: yesSoftwareX, 2019
PyGran is a simulation and analysis toolkit designed for particle systems with emphasis on discrete element method (DEM) simulation. PyGran enables DEM programmers to develop computational tools and perform interactive analysis of granular systems in ...
Andrew Abi-Mansour
doaj   +1 more source

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