Rigidity‐tunable nanovesicle (P‐Pm) with mechanically induced adjuvanticity toward tumor‐associated macrophages (TAMs) was designed to engineer R848/gp100 antigen ‐loaded nanovaccine (P@Rg‐Pm), which achieved outstanding anti‐tumor outcomes in both therapeutic and preventive model of B16‐F10 melanoma.
Bangyue Luo, Liyan Qiu
wiley +1 more source
Cell-Free but potent: Antimicrobial potential of Lactobacillus supernatants against multidrug-resistant pathogens. [PDF]
Cangui-Panchi SP +10 more
europepmc +1 more source
CFP/PC@MnO2 hydrogel integrates ROS scavenging, oxygen delivery, oxidative stress reduction, immunomodulation, and photothermal antibacterial properties. The incorporation of PC@MnO2 NPs endows the hydrogel with multiple functional advantages tailored to the pathological microenvironment of diabetic wounds, including efficient ROS clearance, mitigation
Zhi Xu +9 more
wiley +1 more source
<i>Enterococcus mundtii</i> CRL35 as a Dual-Route Treatment for Cutaneous Leishmaniasis: Preclinical Safety and Efficacy Assessment. [PDF]
Occhionero MA +9 more
europepmc +1 more source
Endothelin receptor type A (EDNRA) and the Hippo/YAP pathway form a self‐reinforcing loop that sustains triple‐negative breast cancer. EDNRA activates YAP through Gαq/11–Rho/ROCK–LATS signaling, while YAP/TEAD4 reciprocally drives EDNRA transcription.
Zehao Hong +10 more
wiley +1 more source
Postural orthostatic tachycardia syndrome in adolescents with ME/CFS - a case control study. [PDF]
Leone A +6 more
europepmc +1 more source
Stochastic Entanglement of Deterministic Origami Tentacles For Robust Robotic Grasping
This study introduces an origami tentacle gripper to robustly grasp objects‐in air, underwater, and even in orbital space‐by exploiting a synergy between local, deterministic deformation programming and global, stochastic entanglements. A single origami tentacle can be designed to coil with a simple tendon pull.
Alec Boron +4 more
wiley +1 more source
Integrated Risk Stratification Using Comorbidity Burden, Frailty, and Systemic Inflammation to Predict 30-Day Mortality in Older Emergency Department Patients: A Prospective Cohort Study. [PDF]
Konur K +12 more
europepmc +1 more source
Phase separation emerges during the initial growth of heavily Ni‐ and Ni,Nb‐co‐doped STO thin films, leading to preferential accumulation of Ni and embedded NiOx nanoinclusions in thicker films. Nb co‐doping partially suppresses the ordering of these embedded structures, comprising about 20% of all Ni ions.
Yen‐Po Liu +7 more
wiley +1 more source
<i>Gata4</i> regulates fibroblast migration in a fibroblast-source-dependent manner under physiological matrix stiffness. [PDF]
Zhang Z +11 more
europepmc +1 more source

