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TDP‐43 proteinopathies and neurodegeneration: insights from Caenorhabditis elegans models

The FEBS Journal, Volume 293, Issue 2, Page 348-384, January 2026.
The manuscript explores structural and functional features of TDP‐43 and its worm homologue, TDP‐1, highlighting conserved and divergent structural and functional features. Using genetically engineered C. elegans models, key pathological features of TDP‐43 proteinopathies—including aggregation, neurodegeneration, and motor deficits—are recapitulated ...
Ghulam Jeelani Pir +7 more
wiley +1 more source

Micro‐Computed Tomography Based Whole Block Imaging of Asthma‐Associated Airway Remodeling With Mycobacterium avium‐Induced Cavity Formation: 3‐Dimensional Nondestructive Analysis

Pathology International, Volume 76, Issue 1, January 2026.
Subpleural cavities are characteristic of Mycobacterium avium infections, but the precise route of infection remains unclear. Using merged micro‐computed tomography of multiple formalin‐fixed paraffin‐embedded (FFPE) blocks (merged whole block imaging), we visualized a continuous airway path from the hilum to a subpleural cavity.
Tetsuya Tsukamoto +10 more
wiley +1 more source

Sildenafil (Viagra) corrects F508-CFTR location in nasal epithelial cells from patients with cystic fibrosis [PDF]

, 2004
Robert L. Dormer
openalex +1 more source

Welfare Indicators for Aquaculture Research: Toolboxes for Five Farmed European Fish Species

Reviews in Aquaculture, Volume 18, Issue 1, January 2026.
ABSTRACT Refining approaches to measuring, monitoring and appraising animal welfare in aquaculture research is key to (i) protecting and optimizing it, (ii) documenting the severity of how and when it deviates, and (iii) ensuring good scientific quality, reliable results and reproducibility, amongst other factors.
Chris Noble +50 more
wiley +1 more source

Depletion of the Ubiquitin-binding Adaptor Molecule SQSTM1/p62 from Macrophages Harboring cftr ΔF508 Mutation Improves the Delivery of Burkholderia cenocepacia to the Autophagic Machinery [PDF]