Results 221 to 230 of about 81,604 (317)

CFTR Modulator Response in Nasal Organoids Derived from People with Cystic Fibrosis. [PDF]

Cells
Lo Cicero S, Castelli G, Ceci A, Cerio AM, Blaconà G, Virgulti M, Allushi S, Sette G, Spadaro F, Amato F, Melotti P, Sorio C, Cimino G, Biffoni M, Lucarelli M, Eramo A.   +15 more
europepmc   +1 more source

62* Investigational compound VX-770 potentiated multiple CFTR channel gating mutants in vitro

, 2011
Fredrick Van Goor, Hui Yu, Bill Burton, T. Y. Huang, Dong‐Yuan Cao, J. P. Johnson, Art Urrutia, Jennings F. Worley, Beth J. Hoffman   +8 more
openalex   +1 more source

Characterizing individuals with elevated sweat chloride results in the absence of CFTR variants. [PDF]

Orphanet J Rare Dis
Bhuiyan I, Chou FY, Roberts JM, Franciosi A, Quon BS.   +4 more
europepmc   +1 more source

EPS3.07 Safety, tolerability and pharmacokinetics of the CFTR potentiator FDL176

, 2018
Claudia L. Ordoñez, Jung‐Kiu Chai, Angela Kolodziej   +2 more
openalex   +1 more source

Highly Effective Modulator Therapy in Cystic Fibrosis: Addressing Unusual Variants in the Middle East. [PDF]

Pulm Med
Isse S, Wahla AS, Uzbeck MH, Zoumot Z, Abuzakouk M, Shafiq I.   +5 more
europepmc   +1 more source

P214: Inequities in eligibility for cystic fibrosis modulator therapy based on pathogenic/likely pathogenic CFTR gene variants identified through carrier screening [PDF]

E.M. Armenti, Ashley Cantu-Weinstein, Ning Sun, Xingwu Lu, Katherine Howard, Linyan Meng, Vivienne Souter   +6 more
openalex   +1 more source

Correction of Aberrant Splicing of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Gene by Antisense Oligonucleotides [PDF]

, 1999
Kenneth J. Friedman, Jolanta Kole, Jonathan Cohn, Michael R. Knowles, Lawrence M. Silverman, Ryszard Kole   +5 more
openalex   +1 more source

Identification and pharmacological characterization of a natural folipastatin as a CFTR inhibitor and potential anti-secretory agent in a human colonoid model. [PDF]

BMC Complement Med Ther
Satitsri S, Khumjiang R, Worakajit N, Nutho B, Rungrotmongkol T, Phainuphong P, Kitiyakara T, Rukachaisirikul V, Muanprasat C.   +8 more
europepmc   +1 more source

Clinical and radiographic features of a family with hypochondroplasia owing to a novel Asn540Ser mutation in the fibroblast growth factor receptor 3 gene [PDF]

, 2000
Craen, Margarita, De Paepe, Anne, Leroy, Juliaan, Mortier, Geert, Nuytinck, Lieve, Renard, Jean-Pierre   +5 more
core   +3 more sources

3-(2-Benzyloxyphenyl)isoxazoles and isoxazolines: synthesis and evaluation as CFTR activators

, 2003
Robert Erik Sammelson, Tonghui Ma, Luis J. V. Galietta, A. S. Verkman, Mark J. Kurth   +4 more
openalex   +1 more source