Results 31 to 40 of about 49,535 (243)
Precision Medicine Based on CFTR Genotype for People with Cystic Fibrosis
Pharmacogenomics and Personalized Medicine, 2022 Iram Haq,1,2 Maryam Almulhem,1 Simone Soars,1 David Poulton,2,3 Malcolm Brodlie1,2 1Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK; 2Paediatric Respiratory Medicine, Great North ...
Haq I +4 more
doaj
The road for survival improvement of cystic fibrosis patients in Arab countries
International Journal of Pediatrics & Adolescent Medicine, 2015 Cystic fibrosis (CF) is a lethal, monogenic disorder that affects multiple organ sys-tems of the body. The incidence has been described before in the Middle East to be 1 in 2000 to 1 in 5800 live births, and the median survival was estimated to be from ...
Hanaa Banjar, Gerhild Angyalosi
doaj +1 more source
Biology Open, 2021 Claudin (Cldn)-10 tight junction (TJ) proteins are hypothesized to form the paracellular Na+ secretion pathway of hyposmoregulating mummichog (Fundulus heteroclitus) branchial epithelia.
Chun Chih Chen +4 more
doaj +1 more source
Synthesis of new pyrazole-pyrimidone derivatives as CFTR potenziators
, 2022 reservedIn questa tesi è presentata la sintesi di un gruppo di composti derivanti da K014X, il cui nucleo pirazolo-pirimidonico è stato visto essere particolarmente efficace nel modulare CFTR, e dunque potenzialmente utile nel trattamento di alcune ...
VIZZON, GIULIA
core
CFTR Modulator Therapy for Rare CFTR Mutants
, 2022 Cystic fibrosis (CF), the most common genetic disease among the Caucasian population, is caused by mutations in the gene encoding for the CF transmembrane conductance regulator (CFTR), a chloride epithelial channel whose dysfunction results in severe ...
Alessandra Ghigo +3 more
core +1 more source
H+ és HCO3- transzporterek szabályozása humán pancreas ductus sejtekben = Regulation of H+ and HCO3-Transporters in Human Pancreatic Duct Cells [PDF]
, 2009 A pancreas nedvben található HCO3- ionok kiválasztásáért a pancreas ductus sejtek felelősek. Jelen pályázatban célul tűztük ki, hogy molekuláris biológiai, transzdukciós és mikrofluorescens technikák felhasználásával megértsük a HCO3- szekréció ...
Rakonczay, Zoltán
core +1 more source
FUNCIÓN PULMONAR EN FIBROSIS QUÍSTICA
Neumología Pediátrica, 2022 La fibrosis quística (FQ) es una enfermedad hereditaria autosómica recesiva, causada por la mutación del gen que codifica la proteína CFTR (cystic fibrosis transmembrane conductance regulator), afecta varios órganos, pero la enfermedad pulmonar es la ...
Hortensia Barrientos
doaj +1 more source
Journal of the Belgian Society of Radiology, 2022 Objectives: Cystic fibrosis transmembrane conductance regulator (CFTR) modulator therapy effects on respiratory function, pulmonary exacerbations and quality of life have been well documented. However, CFTR modulator therapy effects on sinus disease have
Corrado Tagliati +10 more
doaj +1 more source
Advanced Healthcare Materials, EarlyView.Engineered red blood cell‐derived extracellular vesicles (eRBCEVs) are synthesized via controlled microfluidic assembly from native RBC lipids, enabling tunable encapsulation of proteins, nucleic acids, nanoparticles, and viral vectors. The platform demonstrates reproducible nanoscale architecture, preserved membrane composition, and functional cargo ...
Chiranth K. Nagaraj +23 more
wiley +1 more source