Results 31 to 40 of about 25,633 (243)
Análise de glicocorticosteróides por CG-EM: uma nova abordagem de derivatização para o controle de dopagem no esporte [PDF]
Química Nova, 2002 Glucocorticosteroids (CT) show a powerful anti-inflammatory effect. In view of this, they are extensively used in sports medicine, but their misuse (systemic administration) can lead to severe injuries on athletes and has been restricted by the IOC in recent years.
Pereira, Henrique M. G. +3 more
openaire +4 more sources
Quantification of morphology of canine circumanal gland tumors: a fractal based study
European Journal of Histochemistry, 2016 Circumanal gland tumors are very common neoplasms of dogs. Their classification relies on microscopic examination and is further supported by a few immunohistochemical markers that help indicate their prognosis.
I.C. Šoštarić-Zuckermann +7 more
doaj +1 more source
IDENTIFICAÇÃO POR CG-EM E ANÁLISE COMPORTAMENTAL, VIA ACP, DE HPA E SUAS FONTES NO RIACHO ALGODOAIS -SUAPE/PE [PDF]
Anais do XX Congresso Brasileiro de Engenharia Química, 2015 RESUMO – Os Contaminantes Emergentes (CE) tem contribuido no aumento da poluicao ambiental, sobretudo em recursos hidricos, sendo estes caracterizados por se apresentarem em baixas concentracoes, μg.L– pg.L, porem alta persistencia e toxicidade. Dentre os CE, os Hidrocarbonetos Policiclicos Aromaticos (HPA) sao compostos orgânicos com dois ou mais ...
D. P. SOUZA +5 more
openaire +1 more source
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus
FEBS Open Bio, EarlyView.BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima +7 more
wiley +1 more source
Validação de método analítico por ELL-CG-EM para detecção de trialometanos decorrentes da cloração de águas contendo Microcystis [PDF]
Engenharia Sanitaria e Ambiental, 2019 RESUMO Estudos demonstram que a utilização do cloro em estações de tratamento de água (ETA) pode contribuir para a formação de subprodutos orgânicos halogenados indesejados, tais como os trialometanos (TAM), quando há presença de matéria orgânica algogênica, composta de algas e cianobactérias. A Microcystis aeruginosa é uma espécie de cianobactéria com
Elton Santos Franco +7 more
openaire +3 more sources
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Onasemnogene abeparvovec (OA) is an AAV9‐based gene therapy for spinal muscular atrophy type I (SMA I). Real‐world outcomes show increased response variability compared to clinical trials, and follow‐up data beyond 12–18 months are limited.
Marika Pane +43 more
wiley +1 more source
Cracking the Code: Genotype–Phenotype Correlation Models in Sarcoglycanopathies
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Sarcoglycanopathies are among the most severe limb‐girdle muscular dystrophies (LGMD), though milder presentations have been described. These diseases are primarily caused by missense variants, but the limited predictability of their effect on protein maturation, complex formation, and transport has hindered reliable genotype ...
Leonela Luce +72 more
wiley +1 more source
A CONTABILIDADE GERENCIAL NOS EVENTOS ENANPADS DE 2004 A 2008
ABCustos, 2009 As pesquisas em Contabilidade Gerencial (CG) publicadas nos periódicos internacionais, nos últimos dez anos, apontam para o tema Sistema de Controle Gerencial (SCG) como o preferido pelos seus autores. Com vistas a relevância desses estudos desenvolvidos
Elisson Alberto Tavares Araújo +2 more
doaj +1 more source
Safety and Tolerability of Givinostat: Evidence From Real‐World and Clinical Practice
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective The aim of our study was to establish the prevalence of adverse events in a real‐world setting in boys living with Duchenne muscular dystrophy (DMD) treated with givinostat as part of an Expanded Access Program (EAP) in Italy. Methods The cohort included 90 ambulant boys, with age when treatment started between 6 and 23 years (mean ...
Marika Pane +19 more
wiley +1 more source