Results 31 to 40 of about 6,360,558 (232)

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Quantification of morphology of canine circumanal gland tumors: a fractal based study

open access: yesEuropean Journal of Histochemistry, 2016
Circumanal gland tumors are very common neoplasms of dogs. Their classification relies on microscopic examination and is further supported by a few immunohistochemical markers that help indicate their prognosis.
I.C. Šoštarić-Zuckermann   +7 more
doaj   +1 more source

Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus

open access: yesFEBS Open Bio, EarlyView.
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima   +7 more
wiley   +1 more source

Efeitos dos exercícios de dança com videogame nos fatores intrínsecos relacionados a quedas em idosas da comunidade [PDF]

open access: yes, 2016
Orientador : Anna Raquel Silveira GomesTese (doutorado) - Universidade Federal do Paraná, Setor de Ciências Biológicas, Programa de Pós-Graduação em Educação Física. Defesa: Curitiba, 29/07/2016Inclui referências : f.
Rodrigues, Elisângela Valevein
core   +1 more source

Study of 3D Avatars that can be used for Public Relations Strategies and Video Teaching Materials [PDF]

open access: yes, 2021
近年、様々なメディアでコンピュータ・グラフィック(以下CG)を目にする機会が増えた。技術の発展に伴い、実物よりも魅力的に見せたり、現実では考えられない表現方法を用いることで、広告やエンターテイメントを中心とした幅広い業界でその需要が拡大している。動画配信サイトYouTube では、2013年頃から自ら制作した動画を配信するYouTuber が登場し、一般にも広く認知されるようになったが、それに対して2017年になると、バーチャルYouTuber(以下VTuber)と呼ばれる、CG のアバター(1 ...
102151, 永溪, 晃二
core   +1 more source

Safety and Tolerability of Givinostat: Evidence From Real‐World and Clinical Practice

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The aim of our study was to establish the prevalence of adverse events in a real‐world setting in boys living with Duchenne muscular dystrophy (DMD) treated with givinostat as part of an Expanded Access Program (EAP) in Italy. Methods The cohort included 90 ambulant boys, with age when treatment started between 6 and 23 years (mean ...
Marika Pane   +19 more
wiley   +1 more source

Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach   +23 more
wiley   +1 more source

A CONTABILIDADE GERENCIAL NOS EVENTOS ENANPADS DE 2004 A 2008

open access: yesABCustos, 2009
As pesquisas em Contabilidade Gerencial (CG) publicadas nos periódicos internacionais, nos últimos dez anos, apontam para o tema Sistema de Controle Gerencial (SCG) como o preferido pelos seus autores. Com vistas a relevância desses estudos desenvolvidos
Elisson Alberto Tavares Araújo   +2 more
doaj   +1 more source

Extending Service Beyond Active Duty: Generalizability of Rheumatoid Arthritis Research Conducted Among U.S. Veterans

open access: yesArthritis Care &Research, Accepted Article.
Biomedical research involving United States Veterans continues to advance healthcare beyond the Veterans Health Administration. This is particularly true in rheumatoid arthritis (RA), where Veteran‐centric research has uncovered novel insights into pathogenesis, risk factors, and disease manifestations, informing clinical care and research across both ...
Austin M. Wheeler   +20 more
wiley   +1 more source

Technology that achieves the Triple Aim: an economic analysis of the BrainPathTM approach  in neurosurgery

open access: yesClinicoEconomics and Outcomes Research, 2017
Sidney P Norton,1 Evan M Dickerson,1 Charles G Kulwin,2 Mitesh V Shah2 1Financial Planning and Analysis, Indiana University Health, Indianapolis, IN, USA; 2Adult Neurosurgery, Goodman Campbell Brain and Spine, Indianapolis, IN, USA Background: The ...
Norton SP   +3 more
doaj  

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