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Requirement of LaeA for sporulation, pigmentation and secondary metabolism in Chaetomium globosum
Fungal Biology, 2021The global regulator LaeA has been confirmed to govern the production of secondary metabolites in fungi. Herein, we examined the role of LaeA in Chaetomium globosum. Similarly as observed in other filamentous, CgLaeA had a significant effect on the secondary metabolism.
Ming Cheng +4 more
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Bioconversion of (+)-valencene in submerged cultures of the ascomycete Chaetomium globosum
Applied Microbiology and Biotechnology, 2004Submerged cultures of the ascomycete Chaetomium globosum oxidised the exogenous sesquiterpene (+)-valencene to nootkatone via the stereoselective generation of alpha-nootkatol. Inhibition experiments suggested that the first introduction of oxygen, the rate-limiting step of the bioconversion, may have been catalysed by a cytochrome-P450-monooxygenase ...
Rüdiger, Kaspera +3 more
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Cytotoxic azaphilone alkaloids from Chaetomium globosum TY1
Bioorganic & Medicinal Chemistry Letters, 2013Three novel azaphilone alkaloids, namely chaetomugilides A-C (1-3), together with three related compounds (4-6) were isolated from the methanol extract of Chaetomium globosum TY1, an endophytic fungus isolated from Ginkgo biloba. Their structures were elucidated on the basis of extensive 1D and 2D NMR as well as HRESI-MS spectroscopic data analysis ...
Xiang, Li +4 more
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Chaetoglobosin Y, a new cytochalasan from Chaetomium globosum
Fitoterapia, 2014Chaetoglobosin Y (1), was isolated from the endolichenic fungal strain Chaetomium globosum (No. 64-5-8-2), along with related six known cytochalasans, chaetoglobosin Fex (2), chaetoglobosin E (3), isochaetoglobosin D (4), chaetoglobosin G (5), cytoglobosin B (6), and cytoglobosin C (7).
Qi-Chang, Zheng +9 more
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Four cytochalasin alkaloids produced by Chaetomium globosum
Tetrahedron Letters, 2020Abstract A new adduct of chaetoglobosin and aureonitol derivative, aureochaeglobosin D, with three new alkaloids cytoglobosin J-L were isolated from the solid culture of an endophytic Chaetomium globosum harbored in Pinellia ternata. The structures were elucidated by detailed spectroscopic analysis.
Lin An +5 more
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Synthesis of β-linked glucosaccharides by extracts of Chaetomium globosum
Biochimica et Biophysica Acta, 1954Cell-free extracts of mycelium of Chaetomium globosum, grown under specified conditions, were shown to cause dissimilation of cellobiose into glucose and a trisaccharide, which by chemical and physical tests was identified as cellotriose. In the presence of notatin (glucose oxidase) the synthesis proceeded further and certain simple oligosaccharides ...
H W, BUSTON, A, JABBAR
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Spore Dispersal in Chaetomium globosum (Kunze)
Nature, 1961IN the genus Chaetomium the fruit-body, a perithecium, is ornamented with a large number of apical hairs which are either spirally coiled or dichotomously branched. The ascospores are released within the perithecium by breakdown of the ascal walls and the spores ooze out of the ostiole and either form a spore tendril or become entrapped in the apical ...
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Germination of Chaetomium globosum ascospores on hardwoods
Transactions of the British Mycological Society, 1979The sapwood of Tilia europaea L. was found to possess a substance capable of inhibiting germination of ascospores of Chaetomium globosum Kunze ex Fr. The inhibitory substance could be leached from sapwood blocks placed end grain in contact with water agar. Volatile activity of the substance was also demonstrated after oven sterilization of the wood.
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Biotransformation of pseudolaric acid B by Chaetomium globosum
Process Biochemistry, 2011Pseudolaric acid B (1) is a natural product with potent antifungal activity. We discovered that pseudolaric acid B did not kill but only suppress the growth of the filamentous fungus Chaetomium globosum. It was proposed that pseudolaric acid B was converted to metabolites with decreased antifungal activities.
Xing Zhang +6 more
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SUGAR ABSORPTION BY CHAETOMIUM GLOBOSUM
New Phytologist, 1962SummaryThe absorption of the sugars, glucose and fructose, by Chaetomium globosum does not involve an accumulation against an internal concentration but is associated with immediate assimilation. The process is sensitive to the presence of inhibitors, anaerobiosis, and to the concentration supplied.
J. H. WALSH, J. L. HARLEY
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