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An evaluation of benznidazole as a Chagas disease therapeutic

Expert Opinion on Pharmacotherapy, 2019
Introduction: As benznidazole is the first-line treatment for patients with Chagas disease, rational chemotherapy strategies are required based on the critical analysis of the evidence on the relevance and applicability of this drug at different disease ...
I. S. Caldas, E. G. Santos, R. Novaes
semanticscholar   +1 more source

Chagas disease in Mexico

Parasitology Today, 1988
Mexico - the northernmost country of Latin America - has long been thought to have an unusually low prevalence of Chagas disease compared with other Latin American countries. This has seemed unusual because of the large number of vector species and subspecies reported from the country, and the social and ecological conditions that seem to parallel ...
I De Haro Arteaga   +2 more
openaire   +3 more sources

Chagas Heart Disease

2003
American trypanosomiasis and its etiologic agent Trypanosoma cruzi were first described by Carlos Chagas in 1909.12 Chagas single-handedly characterized this new disease in all of its aspects by first discovering the causative agent and its vector and then seeking out and describing human cases of infection ...
James M. Hagar, Shahbudin H. Rahimtoola
openaire   +3 more sources

Poverty, Migration, and Chagas Disease

Current Tropical Medicine Reports, 2021
F. Guhl, J. Ramírez
semanticscholar   +1 more source

Chagas disease in pregnancy

Obstetrics & Gynecology, 1995
Chagas disease is a tropical disease now making its appearance in the United States as more immigration from Latin America occurs. Pregnant women with chronic infection with Trypanosoma cruzi may present with cardiac or gastrointestinal symptoms and transmit the infection to their fetuses.A 32-year-old Mexican woman presented with cardiac symptoms at ...
L A Izquierdo   +4 more
openaire   +3 more sources

AIDS and Chagas' Disease

AIDS Patient Care and STDs, 2000
Chagas' disease can reactivate in patients with AIDS and present as a brain mass lesion or an acute diffuse meningoencephalitis indistinguishable from other opportunistic infections or neoplastic processes, such as toxoplasma encephalitis or central nervous system (CNS) primary lymphoma.
openaire   +3 more sources

Autoimmunity and Chagas’ Disease

1989
The protozoan flagellate Trypanosoma cruzi is the causative agent of Chagas’ disease and has been estimated to infect between 10 and 12 million people in Central and South America (WHO 1960). T. cruzi has a complex life cycle involving stages in both a vertebrate and an insect vector host, the reduviid or assassin bugs, members of the subfamily ...
L. Hudson, G. B. Takle
openaire   +3 more sources

Chagas' Disease

New England Journal of Medicine, 2015
Debora, Pellegrini   +2 more
openaire   +5 more sources

Chagas Disease (American Trypanosomiasis)

The APRN and PA’s Complete Guide to Prescribing Drug Therapy, 2019
Tina Nguyen, Muhammad Waseem
semanticscholar   +1 more source

Chagas Disease Vector Control

Triatominae - The Biology of Chagas Disease Vectors, 2021
R. Gürtler, M. Cecere
semanticscholar   +1 more source

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