Results 151 to 160 of about 308,735 (293)

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Chain drive for propeller on a Wright Model A Flyer

, 1908
Close-up view of the chain and drive shaft for one of the propellers on the Wright Model A Flyer. Caption below photograph, A Shaft. C. H. Claudy Ft. Myer photograph album. This photograph is attributed to C. H.
Claudy, C. H.
core  

Design of sprocket tooth profile for composite pitch block chain transmission

Jixie chuandong
ObjectiveThe composite pitch block chain drive is widely used in the cold drawing machine and other similar equipment in the mechanical industry. The block chain has a special structure with different pitches between internal and external links, which is
LU Jianfu, SHOU Qifeng, ZHANG Kefei, ZHOU Zhidi, SHOU Yulai, SUN Bing   +5 more
doaj  

Specialist-Led Care: A Selective Advantage in Supply Chain Management, Collaborative Aggregation, and Scale. [PDF]

Int J Spine Surg
Massel DH, Moss IL, Jacoby DL, Reid MF.
europepmc   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Application-oriented classification and performance analysis of precision linear feed mechanisms for machine tools. [PDF]

Sci Prog
Zhou J, Yu H, He M, Zhang Y, Luan X, Liu Y.   +5 more
europepmc   +1 more source

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

FEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura, Kengo Furuichi, Hiromitsu Akamatsu, Naoki Yamamoto, Sako Keisuke, Akihiko Koshino, Taichiro Minami, Megumi Oshima, Akinori Hara, Norihiko Sakai, Miho Shimizu, Kenta Takahashi, Minako Yamamura, Shin‐ichi Horike, Takiko Daikoku, Kenichi Harada, Yohei Shinmyo, Hiroshi Kawasaki, Takashi Wada, Yasunori Iwata   +19 more
wiley   +1 more source

PERBAIKAN LINI FINISHING DRIVE CHAIN AHM OEM PADA PT FEDERAL SUPERIOR CHAIN MANUFACTURING DENGAN METODE KESEIMBANGAN LINI DAN METHODS TIME MEASUREMENT

, 2013
PT Federal Superior Chain Manufacturing is a motorcycle chains manufacturing company. PT Federal Superior Chain has a problem with the finishing line of drive chain OEM AHM. The finishing work station’s time is imbalance.
Gunawan, Tony, Gozali, Lina, Widodo, Lamto   +2 more
core  

Non-equilibrium plasmon liquid in a Josephson junction chain. [PDF]

Sci Adv
Bubis AV, Vigliotti L, Serbyn M, Higginbotham AP.   +3 more
europepmc   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source