Results 51 to 60 of about 256,334 (280)

Coupling Properties of Chain Drive System under Various and Eccentric Loads

open access: yesInternational Journal of Simulation Modelling, 2020
The chain drive system is a core subsystem of heavy scraper conveyors. During operation, violent oscillations of fluctuating loads on the chain and uneven loads at the two chain sides are observed, thus intensifying chain wear and even causing chain breakage.
W. J. Ren   +4 more
openaire   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Supply Chain Information Systems and Organisational Performance in Economic Turbulent Times

open access: yes, 2015
Supply Chain Information Systems and their impact on organisational performance has been studied by a number of studies. This study seeks to extend this body of knowledge by adopting a fresh lens to explore empirically the relationship between ...
Reid, Iain   +3 more
core  

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

基于多刚体动力学的新型链轮啮合特性分析

open access: yesJixie chuandong, 2008
In order to study the effect of new sprocket for timing roller chain drive,dynamic simulations are carried out respectively about four timing roller chain drive systems in which four sprockets are exploited respectively such as ISO-606 sprocket,JIS-B1802
顾仁涛, 王勇
doaj  

A complex system, agent based model for studying and improving the resilience of production and distribution networks [PDF]

open access: yes, 2007
The very complexity and the extended reach of today’s globe-spanning supply chain networks, the low inventory levels and lack of redundancies required to achieve efficient operations expose businesses to a huge range of unexpected disruptions.
Datta, Partha Priya
core  

α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates

open access: yesFEBS Letters, EarlyView.
Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino   +2 more
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

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