Results 51 to 60 of about 2,211,912 (309)

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

A multicriteria model for assessing item importance and risk using operational data from military supply chains [PDF]

Journal of Defense Analytics and Logistics
Purpose – This paper is motivated by the need to assess the risk profiles associated with the substantial number of items within military supply chains.
Manuel Rossetti, Juliana Bright, Andrew Freeman, Anna Lee, Anthony Parrish   +4 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Computation of power indices [PDF]

, 2002
Power indices are a useful tool for studying voting systems in which different members have different numbers of votes. Many international organisations are organised in this way in order to accommodate differences in size of countries, including the ...
Leech, Dennis
core  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Second Atom-Bond Connectivity Index of Special Chemical Molecular Structures

Journal of Chemistry, 2014
In theoretical chemistry, the second atom-bond connectivity index was introduced to measure the stability of alkanes and the strain energy of cycloalkanes.
Wei Gao, Weifan Wang
doaj   +1 more source

Gourava and Hyper-Gourava Indices of Some Cactus Chains

Journal of the Indonesian Mathematical Society, 2021
The mathematical chemistry deals with applications of graph theory to study the physicochemical properties of molecules theoretically. A topological index of a graph is a numeric quantity obtained from the graph mathematically. A cactus graph is a connected graph in which no edges lie in more than one cycle.
Basavanagoud, B., Policepatil, Shruti
openaire   +3 more sources

Corporate responsibility, supply chain partnership and performance: An empirical examination [PDF]

, 2012
This is the post-print version of the final paper published in International Journal of Production Economics. The published article is available from the link below. Changes resulting from the publishing process, such as peer review, editing, corrections,
Ghobadian, A, Ghobadian, A., Gallear, D, Chen, Weifeng, Gallear, David, Chen, W., Weifeng Chen, David Gallear, Abby Ghobadian, Chen, W, Ghobadian, Abby, Gallear, D.   +11 more
core   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

FEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui, Agnes Banreti, Armelle L. Ernst, Guillaume Leseigneur, Uwe J. Meierhenrich   +4 more
wiley   +1 more source

Computational analysis of degree-based hyper invariants for supramolecular chain

Main Group Metal Chemistry
One of the fundamental amino acids for mammals is l-valine, a glycogen-type amino acid. This is an essential amino acid for the production of proteins.
Zhang Xiujun, Amjad Muhammad, Jamil Muhammad Kamran, Saleem Umair, Ali Haider, Waheed Muhammad   +5 more
doaj   +1 more source