3D Multicellular Scaffold Based Model for Advancing Bone Disorder Research
A scalable 3D multicellular in vitro bone model engineered by integrating osteoblasts, osteoclasts, and endothelial cells on biodegradable scaffolds. The system recapitulates key features of human bone remodeling and disease pathology. As a proof of concept, the model mimics osteogenesis imperfecta, demonstrating its potential as a physiologically ...
Gali Guterman‐Ram +5 more
wiley +1 more source
Location optimization of cold chain logistics parks based on Bayesian probability theory and K-means clustering analysis in China. [PDF]
Wang L, Liu X, Wang X, Jiang Y.
europepmc +1 more source
The integration of photovoltaic (PV) systems into building structures introduces distinct fire risks with critical implications for occupant safety. This review examines the key fire hazards associated with PV implementation and explores mitigation strategies, including flame‐retardant additives.
Florian Ollagnon +7 more
wiley +1 more source
Game theoretic modeling and optimization of competition and collaboration in dual channel electronic waste supply chains. [PDF]
Wang C, Shi J, Wang K.
europepmc +1 more source
NUMCoT: Numerals and Units of Measurement in Chain-of-Thought Reasoning using Large Language Models [PDF]
Ancheng Xu +4 more
openalex +1 more source
A 3D bone scaffold with osteogenic properties and capable of hardening in vivo is developed. The scaffold is implanted in a ductile state, and a phase transformation of the ceramic induces the stiffening and strengthening of the scaffold in vivo. Abstract Calcium phosphate 3D printing has revolutionized customized bone grafting.
Miguel Mateu‐Sanz +7 more
wiley +1 more source
A mathematical modelling for integrated construction and production supply chain network design. [PDF]
Helli SS, Mokhtari H, Dehnavi S.
europepmc +1 more source
Next‐Generation Bio‐Reducible Lipids Enable Enhanced Vaccine Efficacy in Malaria and Primate Models
Structure–activity relationship (SAR) optimization of bio‐reducible ionizable lipids enables the development of highly effective lipid nanoparticle (LNP) mRNA vaccines. Lead LNPs show superior tolerability and antibody responses in rodents and primates, outperforming approved COVID‐19 vaccine lipids.
Ruben De Coen +30 more
wiley +1 more source
Clinical impact of immunoglobulin heavy chain repertoire in mantle cell lymphoma: A study from the Fondazione Italiana Linfomi (FIL) Phase III MCL0208 trial. [PDF]
Ragaini S +23 more
europepmc +1 more source

