Results 61 to 70 of about 2,128,200 (295)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Predicting Healthcare Mutual Fund Performance Using Deep Learning and Linear Regression

International Journal of Financial Studies
Following the COVID-19 pandemic, the healthcare sector has emerged as a resilient and profitable domain amidst market fluctuations. Consequently, investing in healthcare securities, particularly through mutual funds, has gained traction.
Anuwat Boonprasope, Korrakot Yaibuathet Tippayawong   +1 more
doaj   +1 more source

Comparative quality analysis and economic feasibility of solar assisted yogurt processing unit for decentralized dairy value chain [PDF]

, 2023
Syed Nabeel Husnain, Anjum Munir, Waseem Amjad, Faizan Majeed, Oliver Hensel   +4 more
openalex   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Synergistic effect of pH-sensitive PEGylated RG3-chitosan prodrug nanoparticles encapsulated celastrol on pancreatic cancer

Drug Delivery
Celastrol (Cel) is a potential anticancer therapeutic candidate, but its limited practical applicability is due to its low solubility, poor tumor selectivity, and cytotoxicity.
Zheng Zhang, Jiaxing Wang, Xiaofang Li, Lingzhou Zhao, Junwei Zhao, Mengjiao Su, Xiangxiang Wu, Huahui Zeng   +7 more
doaj   +1 more source

Development and Experimental Study of Smart Solar Assisted Yogurt Processing Unit for Decentralized Dairy Value Chain [PDF]

, 2022
Syed Nabeel Husnain, Waseem Amjad, Anjum Munir, Oliver Hensel   +3 more
openalex   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Performance Evaluation of Supply Chains of Polyethylene Pipes Using Fuzzy Network Data Envelopment Analysis [PDF]

Muṭāli̒āt-i Mudīriyyat-i Ṣan̒atī, 2019
Supply chain is a network consists of several parts and their inter-relationships. To achieve continuous improvement in supply chain, it is necessary to continually evaluate supply chain performance.
Saber Shiripour, Ameneh Adib
doaj   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

Starch Characteristics and Amylopectin Unit and Internal Chain Profiles of Indonesian Rice (Oryza sativa)

Foods
Indonesia is arguably a major player in worldwide rice production. Though white rice is the most predominantly cultivated, red, brown, and red rice are also very common.
Juan Giustra Mogoginta, Takehiro Murai, George A. Annor   +2 more
doaj   +1 more source