Results 71 to 80 of about 2,125,493 (294)

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

open access: yesMolecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad   +35 more
wiley   +1 more source

Starch Characteristics and Amylopectin Unit and Internal Chain Profiles of Indonesian Rice (Oryza sativa)

open access: yesFoods
Indonesia is arguably a major player in worldwide rice production. Though white rice is the most predominantly cultivated, red, brown, and red rice are also very common.
Juan Giustra Mogoginta   +2 more
doaj   +1 more source

Smart System for the Optimization of Logistics Performance of the Pruning Biomass Value Chain

open access: yesApplied Sciences, 2018
Agricultural pruning biomass is one of the important resources in Europe for generating renewable energy. However, utilization of the agricultural residues requires development of efficient and effective logistics systems. The objective of this study was
Girma Gebresenbet   +3 more
doaj   +1 more source

New Retail Business Units´ Forms in Value Chains [PDF]

open access: yesBusiness Logistics in Modern Management, 2013
The formal features of a retail business unit are subject to permanent changes. Starting from the detected regularities therein, this paper’s objective is to enrich an informational basis for a detection of new, more adequate forms. The paper initially analyzes the formal features of retail business units and their changeability.
openaire   +2 more sources

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

A decision-making framework for evaluating medical equipment suppliers under uncertainty

open access: yesScientific Reports
The procurement of medical equipment is a critical concern for healthcare organizations striving to deliver comprehensive patient care. Thus, the procurement process, including performance evaluation and selection of medical equipment suppliers, poses a ...
Sirawadee Arunyanart   +1 more
doaj   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Models evaluating reliability of monoand multiproduct chains at industrial enterprise

open access: yesУченые записки Российской академии предпринимательства, 2021
In this article, the problem of risk reliability estimation functioning in production-technological systems of mono- and multiproduct enterprises is reviewed.
M. A. Khalikov, M. A. Nikiforova
doaj  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Sustaining gains in laboratory systems, HIV, malaria, tuberculosis programs amidst declining international funding: Key considerations for health integration

open access: yesSSM - Health Systems
The efforts to eradicate HIV/AIDS, and other diseases of poverty- Malaria and Tuberculosis have consumed a significant proportion of financial allocation for healthcare.
Augustine Onyeaghala, Theophilus Faruna
doaj   +1 more source

Home - About - Disclaimer - Privacy