Results 81 to 90 of about 2,125,493 (294)

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Modeling of the Penultimate Unit Effect in Chain-Growth Copolymerizations

open access: yesInternational Journal of Polymer Science, 2019
The present work addresses the modeling and simulation of the addition of copolymerizations of styrene and methyl methacrylate in batch mode, and the formation of tailored vinyl acetate/acrylic acid copolymers is evaluated through stochastic optimization
Fabricio Machado
doaj   +1 more source

A second monoclinic polymorph of N-(diethylaminothiocarbonyl)-N′-phenylbenzamidine

open access: yesActa Crystallographica Section E, 2011
The asymmetric unit of the title compound, C18H21N3S, contains five molecules. The equivalent bond distances in the five molecules are in excellent agreement, the r.m.s. fit being within 0.007 Å.
Bernd Schröder   +4 more
doaj   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

基于ANSYS的链条抽油机链板可靠性影响因素分析

open access: yesJixie chuandong, 2013
In order to study the structure reliability of the chain drive pumping unit chain plate,the chain plate of the type of LCJ12-5-14 chain drive pumping unit as an example,the analysis is carried out by ANSYS software.On the basis of the reliability ...
黄天成, 吕伦, 张炎, 袁新梅
doaj  

Eliciting and representing a supply chain strategy [PDF]

open access: yes, 2016
Purpose. The purpose of this paper is two-fold: first, to propose a framework that can be used to represent a supply chain strategy for a business unit in a clear and actionable manner; second, to propose a method that can be used to elicit the factual ...
Perez-Franco, Roberto
core  

Topology of Entanglement in Multipartite States with Translational Invariance

open access: yes, 2013
The topology of entanglement in multipartite states with translational invariance is discussed in this article. Two global features are foundby which one can distinguish distinct states.
Chen, Y. C.   +3 more
core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Magnetization plateaus in the spin-1/2 antiferromagnetic Heisenberg model on a kagome-strip chain

open access: yes, 2018
Spin-1/2 Heisenberg model on kagome lattice is a typical frustrated quantum spin system. A basic structure of kagome lattice is also present in kagome-strip lattice in one dimension, where a similar type of frustration is expected.
Morita, K.   +3 more
core   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Home - About - Disclaimer - Privacy