Results 1 to 10 of about 7,880,129 (337)
Biological variation of serum neurofilament light chain [PDF]
Clinical Chemistry and Laboratory Medicine (CCLM), 2021 Objectives The neurofilament light chain (NfL) has emerged as a versatile biomarker for CNS-diseases and is approaching clinical use. The observed changes in NfL levels are frequently of limited magnitude and in order to make clinical decisions based on ...
C. H. B. Hviid +2 more
semanticscholar +3 more sources
Genetic variation in the immunoglobulin heavy chain locus shapes the human antibody repertoire
Nature Communications, 2023 Variation in the antibody response has been linked to differential outcomes in disease, and suboptimal vaccine and therapeutic responsiveness, the determinants of which have not been fully elucidated.
Oscar L. Rodriguez +12 more
doaj +2 more sources
Germline polymorphisms in the immunoglobulin kappa and lambda loci underpinning antibody light chain repertoire variability [PDF]
Nature CommunicationsVariation in antibody (Ab) responses contributes to variable disease outcomes and therapeutic responsiveness, the determinants of which are incompletely understood.
Eric Engelbrecht +13 more
doaj +2 more sources
eLife, 2019 We find that variation in the dbt-1 gene underlies natural differences in Caenorhabditis elegans responses to the toxin arsenic. This gene encodes the E2 subunit of the branched-chain α-keto acid dehydrogenase (BCKDH) complex, a core component of ...
Stefan Zdraljevic +9 more
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Real-World Image Variation by Aligning Diffusion Inversion Chain [PDF]
Neural Information Processing Systems, 2023 Recent diffusion model advancements have enabled high-fidelity images to be generated using text prompts. However, a domain gap exists between generated images and real-world images, which poses a challenge in generating high-quality variations of real ...
Yuechen Zhang +3 more
semanticscholar +1 more source
Measuring Faithfulness in Chain-of-Thought Reasoning [PDF]
arXiv.org, 2023 Large language models (LLMs) perform better when they produce step-by-step,"Chain-of-Thought"(CoT) reasoning before answering a question, but it is unclear if the stated reasoning is a faithful explanation of the model's actual reasoning (i.e., its ...
Tamera Lanham +29 more
semanticscholar +1 more source
Premature termination of the sympathetic chain
Folia Morphologica, 2022 The sympathetic chain serves to distribute visceral efferents and afferents over the entire body. The sympathetic chain courses from the base of the skull to the coccyx and sends branches to distribute along spinal nerves and a number of visceral nerves ...
Y. Mansour, R. J. Kulesza
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The Urinary Bladder is Rich in Glycosphingolipids Composed of Phytoceramides
Journal of Lipid Research, 2022 Glycosphingolipids (GSLs) are composed of a polar glycan chain and a hydrophobic tail known as ceramide. Together with variation in the glycan chain, ceramides exhibit tissue-specific structural variation in the long-chain base (LCB) and N-acyl chain ...
Takashi Watanabe +10 more
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AIP Advances, 2021 We present a study of the conformational transitions of a helical polymer by using coarse-grained molecular dynamics simulations. With focus on the variation of the dihedral angles, we are able to obtain the monomer-level details of the response of the ...
Shuangshuang Zhang +6 more
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Structural and functional restraints on the occurrence of single amino acid variations in human proteins. [PDF]
PLoS ONE, 2010 Human genetic variation is the incarnation of diverse evolutionary history, which reflects both selectively advantageous and selectively neutral change.
Sungsam Gong, Tom L Blundell
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