Results 61 to 70 of about 7,880,129 (337)
Role of relaxation time scale in noisy signal transduction
, 2014 Intracellular fluctuations, mainly triggered by gene expression, are an inevitable phenomenon observed in living cells. It influences generation of phenotypic diversity in genetically identical cells.
Banik, Suman K. +2 more
core +3 more sources
Multiple human herpesvirus-8 infection [PDF]
, 2003 In Malawian patients with Kaposi sarcoma (KS) and their relatives, we investigated nucleotide-sequence variation in human herpesvirus-8 (HHV-8) subgenomic DNA, amplified from oral and blood samples by use of polymerase chain reaction.
Beyari, MM +7 more
core +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Monte Carlo Hamiltonian from Stochastic Basis [PDF]
, 1999 In order to extend the recently proposed Monte Carlo Hamiltonian to many-body systems, we suggest to concept of a stochastic basis. We apply it to the chain of $N_s=9$ coupled anharmonic oscillators.
C.Q. Huang +20 more
core +3 more sources
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Jixie chuandong, 2014 Classification and main categories of slient chain and Hy-Vo silent chain are introduced.Multivariant variation characteristic and development trend of Hy-Vo slient chain are analyzed.Multivariant variation design method based on meshing mechanism and ...
孟繁忠
doaj
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Condensed Matter Physics, 2011 The effects of polymer concentration and chain length on aggregation in associative polymer solutions, are studied using self-consistent field lattice model. Only two inhomogenous morphologies, i.e.
Y.-B. Guan +4 more
doaj +1 more source
Neel to spin-Peierls transition in a quasi-1D Heisenberg model coupled to bond phonons
, 2013 The zero and finite temperature spin-Peierls transitions in a quasi-one-dimensional spin-1/2 Heisenberg model coupled to adiabatic bond phonons is investigated using the Stochastic Series Expansion (SSE) Quantum Monte Carlo (QMC) method.
Pillay, Jason Cornelius +2 more
core +1 more source
bioRxiv, 2016 Motivation In recent years, molecular species delimitation has become a routine approach for quantifying and classifying biodiversity. Barcoding methods are of particular importance in large-scale surveys as they promote fast species discovery and ...
P. Kapli +6 more
semanticscholar +1 more source