Results 71 to 80 of about 7,880,129 (337)

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Understanding Food Loss and Waste—Why Are We Losing and Wasting Food?

Foods, 2019
The Food and Agricultural Organization (FAO) reported that approximately one-third of all produced foods (1.3 billion tons of edible food) for human consumption is lost and wasted every year across the entire supply chain.
Rovshen Ishangulyyev, Sanghyo Kim, Sang Hyeon Lee   +2 more
doaj   +1 more source

Germline polymorphisms and alternative splicing of human immunoglobulin light chain genes

iScience, 2021
Summary: Inference of germline polymorphisms in immunoglobulin genes from B cell receptor repertoires is complicated by somatic hypermutations, sequencing/PCR errors, and by varying length of reference alleles.
Ivana Mikocziova, Ayelet Peres, Moriah Gidoni, Victor Greiff, Gur Yaari, Ludvig M. Sollid   +5 more
doaj   +1 more source

Reduction of Markov chains with two-time-scale state transitions

, 2015
In this paper, we consider a general class of two-time-scale Markov chains whose transition rate matrix depends on a parameter $\lambda>0$. We assume that some transition rates of the Markov chain will tend to infinity as $\lambda\rightarrow\infty$.
Jia, Chen
core   +1 more source

Isotopic variation of parity violation in atomic ytterbium [PDF]

Physical Review A, 2018
The weak force is the only fundamental interaction known to violate the symmetry with respect to spatial inversion (parity). This parity violation can be used to isolate the effects of the weak interaction in atomic systems, providing a unique, low ...
D. Antypas, A. Fabricant, J. Stalnaker, K. Tsigutkin, V. Flambaum, V. Flambaum, D. Budker, D. Budker   +7 more
semanticscholar   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Quantum relaxation after a quench in systems with boundaries

, 2011
We study the time-dependence of the magnetization profile, m_l(t), of a large finite open quantum Ising chain after a quench. We observe a cyclic variation, in which starting with an exponentially decreasing period the local magnetization arrives to a ...
Iglói, Ferenc, Rieger, Heiko
core   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Coexistence of double alternating antiferromagnetic chains in (VO)_2P_2O_7 : NMR study

, 1999
Nuclear magnetic resonance (NMR) of 31P and 51V nuclei has been measured in a spin-1/2 alternating-chain compound (VO)_2P_2O_7. By analyzing the temperature variation of the 31P NMR spectra, we have found that (VO)_2P_2O_7 has two independent spin ...
A. Weisse, A.W. Garrett, D. Beltrán-Porter, D.A. Tennant, D.C. Johnston, G.S. Uhrig, G.S. Uhrig, J. Kikuchi, J.C. Bonner, Jun Kikuchi, K. Damle, Kiyoichiro Motoya, M. Azuma, M. Takigawa, M. Troyer, M.J. Massey, P. Millet, P.T. Nguyen, R.S. Eccleston, S. Sachdev, T. Barnes, T. Kaneko, T. Shimizu, Touru Yamauchi, Van H. Crawford, Y. Furukawa, Yutaka Ueda   +26 more
core   +1 more source