Results 91 to 100 of about 2,894,137 (337)

Glucose promotes cell growth by suppressing branched-chain amino acid degradation [PDF]

, 2018
Dan Shao, Outi Villet, Zhen Zhang, Sung Won Choi, Jie Yan, Julia Ritterhoff, Haiwei Gu, Danijel Djukovic, Danos C. Christodoulou, Stephen C. Kolwicz, Daniel Raftery, Rong Tian   +11 more
openalex   +1 more source

Contractual Chains

Econometrica
This paper develops a model of private bilateral contracting, in which an exogenous network determines the pairs of players who can communicate and contract with each other. After contracting, the players interact in an underlying game with globally verifiable productive actions and externally enforced transfers.
openaire   +2 more sources

Chains, Null-Chains, and CR Geometry [PDF]

Transactions of the American Mathematical Society, 1993
A system of distinguished curves distinct from chains is defined on indefinite nondegenerate CR {\text {CR}} hypersurfaces; the new curves are called null-chains. The properties of these curves are explored, and it is shown that two sufficiently nearby points of any nondegenerate CR {\text {CR}}
openaire   +2 more sources

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

The Effect of Forward Chaining Method towards Self-Help Ability for Wearing Buttoned Clothe for Students with Intellectual Disability in the Grade VII

Jurnal Penelitian dan Pengembangan Pendidikan Luar Biasa, 2017
The purposes of this study were to describe: 1) the ability of self-help in wearing the buttoned shirt before being given the intervention with forward chaining method, 2) the ability of self-help in wearing the buttoned shirt after being given the ...
Arina Rosada Zain, Umi Safiul Ummah, Abdul Huda   +2 more
doaj  

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Central neural circuitry mediating courtship song perception in male Drosophila

eLife, 2015
Animals use acoustic signals across a variety of social behaviors, particularly courtship. In Drosophila, song is detected by antennal mechanosensory neurons and further processed by second-order aPN1/aLN(al) neurons.
Chuan Zhou, Romain Franconville, Alexander G Vaughan, Carmen C Robinett, Vivek Jayaraman, Bruce S Baker   +5 more
doaj   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

SISTEM PAKAR DIAGNOSA PENYAKIT PADA TANAMAN KAKAO MENGGUNAKAN METODE FORWARD CHAINING (STUDI KASUS DINAS PERKEBUNAN INDRAGIRI HILIR)

Sistemasi: Jurnal Sistem Informasi, 2015
Sistem Pakar Diagnosa Penyakit pada Tanaman Kakao Menggunakan Metode Forward Chaining di Dinas Perkebunan Indragiri Hilir. Merupakan  sistem yang bisa memberikan informasi keterangan beberapa jenis dan ciri-ciri penyakit yang mengganggu tanaman kakao ...
Siti Hawa, Abdullah Abdullah, Usman Usman   +2 more
doaj   +1 more source