Results 171 to 180 of about 2,894,137 (337)

HSP70 governs permeability and mechanotransduction in primary human endothelial cells

FEBS Open Bio, EarlyView.
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez, Everton G. Melo, Isadora C. B. Pavan, Percíllia V. S. Oliveira, Luiza B. C. T. Coimbra, Thaís L. S. Araujo   +5 more
wiley   +1 more source

VACmap: an accurate long-read aligner for unraveling complex genomic rearrangements. [PDF]

Nat Commun
Ding H, Sedlazeck FJ, Proukakis C, Morley C, Toffoli M, Schapira AH, Liao Z, Pu L, Zhu S.   +8 more
europepmc   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

A novel peptidoglycan deacetylase modulates daughter cell separation in E. coli. [PDF]

PLoS Genet
Hernández-Rocamora VM, Martorana AM, Belloso A, Ballesteros D, Zaccaria M, Perez AJ, Iorga BI, Abia D, Gray J, Breukink E, Xiao J, Pazos M, Polissi A, Vollmer W.   +13 more
europepmc   +1 more source

The Chain Length Dependence of Helix Formation of the Second Transmembrane Domain of a G Protein-coupled Receptor ofSaccharomyces cerevisiae

, 2002
Fa‐Xiang Ding, David Schreiber, Nathan C. VerBerkmoes, Jeffrey M. Becker, Fred Naider   +4 more
openalex   +1 more source

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

FEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

Restructuring of the Corn Supply Chain in Brazil: Facing the Challenges in Logistics or Regulation of Biotechnology

, 2013
Andréa Leda Ramos de Oliveira, José Maria Ferreira Jardim da Silveira, Oliveira, Andréa Leda Ramos De, Silveira, José Maria Ferreira Jardim Da   +3 more
openalex   +2 more sources

Joint-design of products and supply chain in a context of innovation

, 2022
Brunelle Marche, Vincent Boly, J. Roland Ortt, Laure Morel   +3 more
openalex   +2 more sources

Autophagosome marker, LC3, is released extracellularly via several distinct pathways

FEBS Open Bio, EarlyView.
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito, Masashi Arakawa, Koki Maeda, Eiji Morita   +3 more
wiley   +1 more source

Nomadic Lactobacilli as cell factory for antibiofilm therapy. [PDF]

Front Cell Infect Microbiol
Paul LS, Hameed HC, K V L, Sharma A, Lee J, Shemesh M, Rajasekharan SK.   +6 more
europepmc   +1 more source