Results 61 to 70 of about 2,894,137 (337)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Medieval Jewelry Items from Semenovka Settlement
Поволжская археология, 2016 The article presents results of studying several jewelry items of the Volga Bulgars, collected as stray finds on destroyed Bulgar non-fortified settlements located on an island on Kuybyshev dam lake.
Begovatov Evgeniy A. +1 more
doaj
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Journal of Combinatorial Theory, Series B, 1995 If \(H\) and \(H'\) are subgraphs of \(G\), both isomorphic to subdivisions of \(K_5\) or \(K_{3,3}\), then the following are equivalent: (1) There is a sequence \(H= H_1, H_2,\dots, H_k= H'\) of subgraphs of \(G\), each isomorphic to a subdivision of \(K_5\) or \(K_{3,3}\) and ``slightly'' different from its predecessor; (2) \(H\) and \(H'\) are not ``
Robertson, N., Seymour, P., Thomas, R.
openaire +1 more source
FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Expert System for Determination of Type Lenses Glasses Using Forward Chaining Method
Scientific Journal of Informatics, 2016 One of the branches of computer science that is widely used by humans to help her work is the establishment of an expert system. In this study we will design an expert system for determining the type of spectacle lenses using a forward chaining method ...
Atikah Ari Pramesti +2 more
doaj +3 more sources
, 2018 This book covers the classical theory of Markov chains on general state-spaces as well as many recent developments. The theoretical results are illustrated by simple examples, many of which are taken from Markov Chain Monte Carlo methods. The book is self-contained, while all the results are carefully and concisely proven.
Douc, Randal +3 more
openaire +3 more sources
Mediterranean Journal of Hematology and Infectious Diseases, 2018 Light chain (AL) amyloidosis is caused by a usually small plasma-cell clone that is able to produce the amyloidogenic lights chains. They are able to misfold and aggregate, deposit in tissues in the form of amyloid fibrils and lead to irreversible organ dysfunction and eventually death if treatment is late or ineffective.
Milani P., Merlini G., Palladini G.
openaire +4 more sources
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source