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Anticancer activities of novel chalcone and bis-chalcone derivatives
Bioorganic & Medicinal Chemistry, 2006A series of novel chalcones and bis-chalcones containing boronic acid moieties has been synthesized and evaluated for antitumor activity against the human breast cancer MDA-MB-231 (estrogen receptor-negative) and MCF7 (estrogen receptor-positive) cell lines and against two normal breast epithelial cell lines, MCF-10A and MCF-12A.
Peng Huang +5 more
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Anti‐tumorigenic chalcones [PDF]
STEM CELLS, 1994 On the basis of our recent findings that licochalcone A isolated from Xin-jiang licorice showed anti-inflammatory and anti-tumorigenic activities, we synthesized more than 40 chalcone derivatives to examine their anti-tumorigenic activities. In vitro inhibitory activity against phosphorylation of phospholipids promoted by tetradecanoylphorbol-13 ...
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Chemistry of Heterocyclic Compounds, 1971
Previously undescribed aromatic α-keto oxides have been obtained by the epoxidation of chalcones with alkaline hydrogen peroxide in methanolic solution.
V. F. Belyaev, N. M. Yatsevich
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Previously undescribed aromatic α-keto oxides have been obtained by the epoxidation of chalcones with alkaline hydrogen peroxide in methanolic solution.
V. F. Belyaev, N. M. Yatsevich
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, 2021
In nature, chalcones are extensively available in edible plants and as starting components of flavonoids. Based on the presence of reactive bi-electrophilic group and the keto-vinyl spacer, chalcones and their metal complexes possess significant ...
R. Kaushal, Mandeep Kaur
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In nature, chalcones are extensively available in edible plants and as starting components of flavonoids. Based on the presence of reactive bi-electrophilic group and the keto-vinyl spacer, chalcones and their metal complexes possess significant ...
R. Kaushal, Mandeep Kaur
semanticscholar +1 more source
Chalcones and Bis-Chalcones Analogs as DPPH and ABTS Radical Scavengers
Letters in Drug Design & Discovery, 2021Background:A number of synthetic scaffolds, along with natural products, have been identified as potent antioxidants. The present study deals with the evaluation of varyingly substituted, medicinally distinct class of compounds “chalcones and bis-chalcones” for their antioxidant potential.Methods:In vitro radical scavenging activities were performed on
Adebayo Tajudeen Bale +9 more
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Chemical sensing of chalcones by voltammetry: trans-Chalcone, cardamonin and xanthohumol
Electrochimica Acta, 2013Abstract Xanthohumol (XN) and cardamonin (CD) belong to the chemical class of chalcones which are phenolic compounds of large interest due to their health promoting properties. In the present work, their electrochemical behavior on a hanging mercury drop electrode (HMDE) is compared to trans -chalcone by means of cyclic voltammetry (CV).
Tavares, E.M. +8 more
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An Amine‐Promoted Aziridination of Chalcones.
ChemInform, 2006AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Mei-Xin Zhao +3 more
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Polarographic reduction of chalcones [PDF]
Bulletin of the Academy of Sciences of the USSR Division of Chemical Science, 1972 1. The influence of substituents on the polarographic reduction of chalcones and their vinylogs is exerted chiefly according to an inductive mechanism, and as a result of this decreased rapidly with increasing length of the chain of double bonds. 2.
V. F. Kucherov +2 more
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Coupling–Isomerization Synthesis of Chalcones
Chemistry – A European Journal, 2006AbstractThe Sonogashira coupling of electron‐deficient (hetero)aryl halides 1 and (hetero)aryl or alkenyl 1‐propargyl alcohols 2 does not terminate at the stage of the expected internal propargyl alcohols, but rather gives rise to the formation of α,β‐unsaturated ketones 3 with a variety of acceptor substituents.
Thomas Müller +2 more
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Antimalarial Activity of Ferrocenyl Chalcones.
ChemInform, 2002AbstractFor Abstract see ChemInform Abstract in Full Text.
Wu, X., Wilairat, P., Go, M.-L.
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