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Polymorphism and conformerism in chalcones
CrystEngComm, 2016Herein two solid state phenomena have been observed in two chalcones. Firstly, polymorphism has been found in (E)-1-(2-aminophenyl)-3-(3,4,5-trimethoxyphenyl)prop-2-en-1-one (1). This compound crystallizes with only one conformer rather than three in the known reported structure. In the polymorphs, the conformation of the phenyl ring bonded to carbonyl
Felipe T. Martins +3 more
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The reaction of chalcone with phosphonates
Tetrahedron, 1971Abstract Chalcone reacts with the anions of triethyl phosphonoacetate (I) and diethyl benzylphosphonate (IV)—depending on the operating conditions—either in a Michael or a Wittig-Horner reaction.
Ernst D. Bergmann, A. Solomonovici
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Inhibiting Firefly Bioluminescence by Chalcones
Analytical Chemistry, 2017Chalcone refers to an aromatic ketone and an enone that constitutes the central core for various important biological compounds in drug discovery. Moreover, the firefly luciferase (Fluc) as the bioluminescent reporter has been widely used in life science research and high-throughput screening (HTS).
Huateng Zhang +8 more
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Molecular Crystals and Liquid Crystals, 2002
The photoisomerization behavior of benzylidene-acetophenones known as chalcones, was studied. We synthesized the chalcone derivatives that have ether groups at 4 and 4′ positions. Due to the electron donating ability of the ether oxygen, the bond order of the single bond between two phenyl ring of the chalcone strengthened, which eventually increased ...
Kyung-Hoon Jung +2 more
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The photoisomerization behavior of benzylidene-acetophenones known as chalcones, was studied. We synthesized the chalcone derivatives that have ether groups at 4 and 4′ positions. Due to the electron donating ability of the ether oxygen, the bond order of the single bond between two phenyl ring of the chalcone strengthened, which eventually increased ...
Kyung-Hoon Jung +2 more
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Antiangiogenic effects of flavonoids and chalcones
Pharmacological Research, 2008Angiogenesis, the development of new blood vessels from the existing vasculature, is essential in normal developmental processes. Uncontrolled angiogenesis is a major contributor to a number of disease states such as inflammatory disorders, obesity, asthma, diabetes, cirrhosis, multiple sclerosis, endometriosis, AIDS, bacterial infections and ...
Jan Mojzis +4 more
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Advances in Chalcones with Anticancer Activities
Recent Patents on Anti-Cancer Drug Discovery, 2014Chalcones are naturally occurring compounds exhibiting broad spectrum biological activities including anticancer activity through multiple mechanisms. Literature on anticancer chalcones highlights the employment of three pronged strategies, namely; structural manipulation of both aryl rings, replacement of aryl rings with heteroaryl scaffolds ...
N.S.H.N. Moorthy +6 more
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Structural study on chalcone derivatives
Synthetic Metals, 1994Abstract Crystal structures of several SHG-active chalcone derivatives were determined by X-ray analysis. The phase-matching direction of a 1-(3-thienyl)-3-(4-chlorophenyl)-2-propen-1-one crystal is discussed by relating to its molecular packing in the crystal.
K. Kozawa +3 more
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Chalcones, Aurones and Dihydrochalcones
1975This chapter will treat three small groups of flavonoids: chalcones, dihydrochalcones and aurones. In the case of chalcones and aurones, placing them together in the same chapter reflects their traditional treatment as ‘anthochlor’ pigments. This term was originally coined to identify a group of yellow pigments which turned red in the presence of ...
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Enzymatic halogenation of chalcones
2006Silvestrini A, Giardina B, Vitali A
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