Results 281 to 290 of about 53,724 (334)

Pyrazolyl amide-chalcones conjugates: Synthesis and antikinetoplastid activity. [PDF]

Naunyn Schmiedebergs Arch Pharmacol
Agarwal DS, Beteck RM, Mabille D, Caljon G, Legoabe LJ.   +4 more
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Chalcones and Bis-Chalcones Analogs as DPPH and ABTS Radical Scavengers

Letters in Drug Design & Discovery, 2021
Background:A number of synthetic scaffolds, along with natural products, have been identified as potent antioxidants. The present study deals with the evaluation of varyingly substituted, medicinally distinct class of compounds “chalcones and bis-chalcones” for their antioxidant potential.Methods:In vitro radical scavenging activities were performed on
Adebayo Tajudeen Bale, Uzma Salar, Khalid Mohammed Khan, Sridevi Chigurupati, Tolulope Fasina, Farman Ali, Muhammad Ali, Sitansu Sekhar Nanda, Muhammad Taha, Shahnaz Perveen   +9 more
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Synthesis, reactions and application of chalcones: a systematic review.

Organic and biomolecular chemistry, 2023
Chalcones are a group of naturally occurring compounds that have biological effects that include anti-inflammatory, anti-cancer, and antibacterial properties.
Mona A. Shalaby, Sameh Ahmed Rizk, A. Fahim   +2 more
semanticscholar   +1 more source

Naturally occurring prenylated chalcones from plants: structural diversity, distribution, activities and biosynthesis.

Natural product reports (Print), 2021
Covering: up to July 2020Naturally occurring chalcones carrying up to three modified or unmodified C5-, C10-, and C15-prenyl moieties on both rings A and B as well as at the α- and β-carbons are widely distributed in plants of the families of Fabaceae ...
K. Zhou, Song Yang, Shu‐Ming Li
semanticscholar   +1 more source

Systematic review on anti-diabetic properties of chalcones.

Current Medicinal Chemistry, 2020
The use of anti-diabetic drugs has been increasing worldwide and the evolution of therapeutics has been enormous. Still, the currently available anti-diabetic drugs do not present the desired efficacy and are generally associated with serious adverse ...
Sónia Rocha, D. Ribeiro, E. Fernandes, M. Freitas   +3 more
semanticscholar   +1 more source

ChemInform Abstract: Bioactivities of Chalcones

ChemInform, 1999
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Michael A. Beazely, D. W. Elias, N. M. Kandepu, Jonathan R. Dimmock   +3 more
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Structure of a chalcone

Acta Crystallographica Section C Crystal Structure Communications, 1993
1-(7-Hydroxy-2,2-dimethylchroman-6-yl)-3-phenyl-2-propen-1-one, C 20 H 20 O 3 , M r =308.38, P2 1 /a, a=12.002 (2), b=11.013 (2), c=12.652 (3) A, β=106.24 (3) o , V=1605.6 A 3 , Z=4, D m =1.26 (2), D x =1.275 Mg m -3 , λ(Mo Kα)=0.71069 A, μ=0.079 mm -1 , F(000)=656, T=293 K, R=0.037, wR=0.034 for 892 reflections with I>3σ(I).
ALEX, G, SRINIVASAN, S, KRISHNASAMY, V, SURESH, RV, IYER, R, IYER, PR   +5 more
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Novel chalcones derivatives with potential antineoplastic activity investigated by docking and molecular dynamics simulations

Journal of Biomolecular Structure and Dynamics, 2020
Glioblastoma is an aggressive primary tumor of the central nervous system (CNS). Is the most aggressive among infiltrative gliomas arising from the CNS.
R. D. A. M. Neto, Cleydson B. R. Santos, S. V. C. Henriques, L. D. Machado, J. Cruz, C. D. da Silva, L. Federico, E. H. Oliveira, M. D. de Souza, Patrícia N B da Silva, C. Taft, I. Ferreira, Madson R F Gomes   +12 more
semanticscholar   +1 more source

Pyrazole-coumarin and pyrazole-quinoline chalcones as potential antitubercular agents.

Archiv der Pharmazie, 2020
Pyrazole, coumarin, and quinoline are medicinally important moieties. In this study, two series of novel pyrazole-coumarin chalcones and pyrazole-quinoline chalcones were synthesized using multiple-step reactions.
Gautam Kumar, Vagolu Siva Krishna, D. Sriram, S. Jachak   +3 more
semanticscholar   +1 more source