Results 131 to 140 of about 2,443,514 (252)

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Pre-subduction of the Caroline Plateau intensifies lithospheric hydration in the southern Mariana Trench

open access: yesCommunications Earth & Environment
The subduction of oceanic plateaus significantly reshapes subduction systems, yet its impact on lithospheric hydration prior to subduction is not well understood. Here we investigate these processes as the Caroline Plateau approaches the southern Mariana
Enyuan He   +8 more
doaj   +1 more source

The Weekly Challenger, December 18, 1976

open access: yes, 1976
The December 18, 1976, issue of The Weekly Challenger.https://digitalcommons.usf.edu/challenger/1404/thumbnail ...
The Weekly Challenger, et al
core  

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

The Weekly Challenger, October 6, 1973

open access: yes, 1973
The October 6, 1973, issue of The Weekly Challenger.https://digitalcommons.usf.edu/challenger/1708/thumbnail ...
The Weekly Challenger, et al
core  

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

The Weekly Challenger, December 26, 1981

open access: yes, 1981
The December 26, 1981, issue of The Weekly Challenger.https://digitalcommons.usf.edu/challenger/1460/thumbnail ...
The Weekly Challenger, et al
core  

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

Whole Genome Sequence of Dermacoccus abyssi MT1.1 Isolated from the Challenger Deep of the Mariana Trench Reveals Phenazine Biosynthesis Locus and Environmental Adaptation Factors. [PDF]

open access: yesMar Drugs, 2020
Abdel-Mageed WM   +10 more
europepmc   +1 more source

The Weekly Challenger, August 8, 1992

open access: yes, 1992
The August 8, 1992, issue of The Weekly Challenger.https://digitalcommons.usf.edu/challenger/1447/thumbnail ...
The Weekly Challenger, et al
core  

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