Results 151 to 160 of about 8,553,581 (297)

Challenges

Gastroenterology, 1972
openaire   +2 more sources

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Improving Health Care Services for Autistic Young Adults: Development and Use of a Self-Reported Health Care Transition Readiness Assessment. [PDF]

Int J Lang Commun Disord
Cheak-Zamora NC, Boccardi L, Bertucci G.
europepmc   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Evaluating AI adoption challenges in healthcare using a Multi-Criteria Decision-Making approach: implications for predictive risk analytics. [PDF]

Front Artif Intell
Venugopal P, Garg P, Prakash C, Kumar S, Gupta N.   +4 more
europepmc   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Bridging the gap between public health, academia and policy. [PDF]

BMJ Glob Health
Christen P, Dawa J, Ahmed O, Akinyi F, Ameyo Masakhwe B, Bekalo DB, Biwot C, Bosire AB, Charles G, Gathoni V, Gaythorpe KAM, Geoffrey G, Gowa S, Hamumy FS, Kagiri H, Kamundia G, Kamunya S, Kariuki P, Khalayi L, Kombe I, Kwamboka P, Liétar P, Likalamu N, Lugonzo B, Mariita V, Masinde A, Mbithi M, McCabe R, Monari FN, Ondicho Motiri F, Muchiri AM, Mudamba A, Mugo PW, Mutono N, Muriithi M, Musasia R, Mutunga M, Mwangi W, Nalwa J, Ngeno KI, Nyaberi JM, Nzoka PM, Ojal J, Okech T, Okunga E, Omondi E, Osoro J, Osoro P, Patel A, Sayianka S, Shigoli T, Silali C, Thendu MM, van Elsland SL, Wanjiku KA, Muchemi P, Whittles LK, Winskill P, Ombajo LA, Thumbi SM, Watson OJ.   +60 more
europepmc   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

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The Person and the Challenges, 2020
The Person and The Challenges
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