Results 171 to 180 of about 758,941 (258)

Mascarón de Tlaloc en el templo de Quetzalcóatl

open access: yes, 1950
I.O. En el anverso, manuscrito: "XLVII-30", "PIÑA CHAN". V.F.
Román Piña Chan (photographer)
core  

Animal stroke models and outcome evaluation: A review

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Rodents are the preeminent stroke model species. Large animal models exist too, but are poorly standardized. Ischemic and hemorrhagic experimental models are available, with the intraluminal filament model being predominant. Outcomes are evaluated via quantifying subjects' sensorimotor impairment, cognitive memory faculties, degree of cellular ...
Solsa Cariba   +2 more
wiley   +1 more source

1‐Azabicyclo[1.1.0]butanes (ABBs) on the Map: Mechanistic Pathways for Catalytic Ring Opening and Functionalizations

open access: yesAngewandte Chemie, EarlyView.
Catalytic strain‐release ring opening and functionalizations of 1‐azabicyclo[1.1.0]butanes (ABBs) represent a promising strategy for accessing diverse azetidine products. These transformations proceed via polar pathways, radical pathways, and hybrid mechanisms that combine both.
James Shao‐Jiun Yang   +1 more
wiley   +2 more sources

Gente observa el Templo de Quetzalcóatl, vista parcial

open access: yes, 1950
I.O. En el anverso, manuscrito: "XLVII-31". "PIÑA CHAN".
Román Piña Chan (photographer)
core  

Multimodal Characterization of Glymphatic‐Related Magnetic Resonance Imaging Markers in Huntington's Disease: A Multi‐Cohort Retrospective Study

open access: yesAnnals of Neurology, EarlyView.
Objective To characterize magnetic resonance imaging (MRI)‐based glymphatic surrogates in Huntington's disease (HD) using MRI measures of perivascular diffusivity and structural perivascular alterations across multiple large cohorts. Methods We analyzed 2,731 MRI sessions from 880 participants across 3 large retrospective HD cohorts.
Alexia Solomon   +5 more
wiley   +1 more source

Suppression of Peierls Instability in a Metal−Halide Porous Framework

open access: yesAngewandte Chemie, EarlyView.
Peierls distortion in one‐dimensional Pt‐I chains is suppressed by confinement within the periodic electrostatic environment of a porous Cu–I framework. X‐ray crystallography shows equivalent Pt–I distances without bond alternation, and conductivity of the Pt‐I chains is greatly enhanced.
Ning Zhou   +3 more
wiley   +2 more sources

In reply to Walewska et al. [PDF]

open access: yesJ Appl Clin Med Phys
Yang Y, Chan M.
europepmc   +1 more source

Silk Fibroin for Cardiovascular Medical Devices: Review of Material Properties, Applications, and Clinical Potential

open access: yesAdvanced NanoBiomed Research, EarlyView.
Silk fibroin is an attractive natural biomaterial that can be engineered into diverse cardiovascular constructs, including vascular grafts, cardiac patches, heart valves, and stent coatings. Its tunable biological and mechanical properties have driven substantial preclinical progress; however, widespread clinical translation in cardiovascular ...
Mahsa Haghighattalab   +8 more
wiley   +1 more source

1,4‐Brook Rearrangement of β‐Silyl Allylic Alcohols: Trisubstituted Alkenes by Copper‐Mediated Stereoretentive ipso‐Substitution Reactions

open access: yesAngewandte Chemie, EarlyView.
To fully leverage the power of the ruthenium‐catalyzed trans‐hydrosilylation of propargyl alcohols, it was necessary to develop a practical and robust method for the activation of those products that carry the silyl group distal to the hydroxy substituent.
Paul Haf‐Moths   +2 more
wiley   +2 more sources

A DNA G‐Quadruplex‐Targeting Ligand Suppresses c‐MYC Expression: Implications for Gemcitabine‑Resistant Pancreatic Cancer

open access: yesAngewandte Chemie, EarlyView.
PQB‐4, a fluorescent small‐molecule ligand that targets c‐MYC DNA G‐quadruplexes (G4s), showed marked synergy with gemcitabine in resistant PANC‐1 cells (CI = 0.027). In vivo, the ligand reduced tumor weight by 44% in a PANC‐1 xenograft model. These results highlight the therapeutic potential of c‐MYC DNA G4‐targeting ligands for treating gemcitabine ...
Bo‐Xin Zheng   +10 more
wiley   +2 more sources

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