Results 131 to 140 of about 4,075,413 (333)
Landscape of BRAF transcript variants in human cancer
We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda+5 more
wiley +1 more source
LA CONSCIENCIA: ¿UNA REALIDAD NO ALGORÍTMICA?
La consciencia ha vuelto a ser centro de atención de psicólogos y científicos en general, y no ha dejado de serlo para muchos filósofos. Sin embargo, no hay acuerdo en la manera de entenderla.
JUAN DIEGO LOPERA ECHAVARRÍA
doaj
Chances of Recovery in Asylums [Die Heilungsaussichten in der Innenanstalt]. (Neur. Cbl., No. 15, 1908.) Alt [PDF]
Hamilton C. Marr
openalex +1 more source
Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte+10 more
wiley +1 more source
On the manufacture of portland cement from alkali waste after treatment by the chance sulphur recovery process [PDF]
Charles Spackman
openalex +1 more source
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song+11 more
wiley +1 more source
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton+17 more
wiley +1 more source
Sérendipité et sciences sociales : enseignements d’une expérience vécue
Unforeseen data is not only likely to disturb the researcher too sure of his theories, but it can also save the researcher when dealing with a jumble of elements for which he is unable to account as a whole because it evokes incomprehensible images. Thus,
Philippe d’Iribarne
doaj
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop+10 more
wiley +1 more source