Results 171 to 180 of about 4,075,413 (333)

Targeting carbonic anhydrase IX/XII prevents the anti‐ferroptotic effect of stromal lactic acid in prostate carcinoma

Molecular Oncology, EarlyView.
In prostate carcinoma, lactic acid, secreted by highly glycolytic cancer‐associated fibroblasts, is imported into tumor cells through the MCT1 transporter and prevents RSL3 and erastin‐induced ferroptosis (A). Targeting of carbonic anhydrase IX/XII, the main extracellular pH regulators, in tumor and stromal cells reduces microenvironmental acidosis and
Elisa Pardella, Giuseppina Comito, Luigi Ippolito, Erica Pranzini, Marta Iozzo, Giulia Gangarossa, Francesca Virgilio, Silvia Bua, Alessio Nocentini, Giada Sandrini, Nicla Lorito, Marina Bacci, Gabriella Nesi, Pietro Spatafora, Sergio Serni, Claudiu T. Supuran, Andrea Morandi, Paola Chiarugi, Elisa Giannoni   +18 more
wiley   +1 more source

The Aesthetics of DADA, a game of chance? [PDF]

Diversitate si Identitate Culturala in Europa
Throughout history, for the new to emerge, there must be a challenge to the old order of a world that seeks to be abolished. It is the law of continuity which, paradoxically, is meant to function periodically through rupture.
Ileana TĂNASE
doaj  

On the Probability of Large Deviations for Sums of Bounded Chance Variables [PDF]

, 1956
Harry Weingarten
openalex   +1 more source

Machine learning for identifying liver and pancreas cancers through comprehensive serum glycopeptide spectra analysis: a case‐control study

Molecular Oncology, EarlyView.
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima, Yuko Takami, Ken Kawabe, Kazuhiro Tanabe, Chihiro Hayashi, Mikio Mikami, Tetsuya Kusumoto   +6 more
wiley   +1 more source

The Chances of Premature Death among Select Lives [PDF]

Edwin James Farren
openalex   +1 more source

Oystein, Ore, Cardano the Gambling Scholar. With a Translation from the Latin of Cardano's Book on Games of Chance, by Sydney Henry Gould. Leinen, IX + 249 Seiten, 29 Abbildungen, 4 Tafeln. Princeton University Press 1953. [PDF]

, 1957
H Buess
openalex   +1 more source

Not a chance [PDF]

Nature, 2009
openaire   +2 more sources

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Urgency overpowers cognitive control by amplifying cognitive processing asymmetries. [PDF]

Atten Percept Psychophys
Krause A, Poth CH.
europepmc   +1 more source

Discussion of “Highway Bridge Live Loads Based on Laws of Chance” [PDF]

, 1957
Raymond Archibald
openalex   +1 more source